| Literature DB >> 21688328 |
Motohiro Akazome1, Masashi Enzu, Koji Takagi, Shoji Matsumoto.
Abstract
A chiral cyclotetrapeptide (1) was synthesized from 2-nitrobenzoic acid and leucine. A single-crystal X-ray of the compound revealed a C(2) -symmetric bowl-shaped structure. The cyclic compound had a unique hydrogen-bonding network composed of three-centered hydrogen bonds and bifurcated hydrogen bonds between NH and CO of anthranilic residue. The NMR spectra and molecular modeling of 1 also suggested the chiral bowl structure.Entities:
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Year: 2011 PMID： 21688328 DOI： 10.1002/chir.20972
Source DB: PubMed Journal: Chirality ISSN： 0899-0042 Impact factor: 2.437