Literature DB >> 2168823

Cytotoxic T cells against herpes simplex virus in Behçet's disease.

K Hamzaoui1, A Kahan, K Ayed, M Hamza.   

Abstract

Lymphocytes from 36 patients with Behçet's disease (20 in remission and 16 in active phase) were stimulated in vitro with herpes simplex virus and then tested for their ability to generate cytotoxic T cell responses to the virus. Significant cytotoxic responses were found. CD4+ and CD8+ subpopulations from the patients in remission generated specific cytotoxic activity against autologous target cells. These observations suggested that CD4+ and CD8+ cytotoxic T cells may have an important host response in herpes virus infection in Behçet's disease.

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Year:  1990        PMID： 2168823      PMCID： PMC1534992          DOI： 10.1111/j.1365-2249.1990.tb05344.x

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  23 in total

1.  A virus-specific CD4+ cell-mediated cytolytic activity revealed by CD8+ cell elimination regularly develops in uncloned human antiviral cell lines.

Authors:  I Bourgault; A Gomez; E Gomard; F Picard; J P Levy; E Gomrad
Journal:  J Immunol       Date:  1989-01-01       Impact factor: 5.422

2.  Differential in vitro activation of CD4+CD8- and CD8+CD4- herpes simplex virus-specific human cytotoxic T cells.

Authors:  M Yasukawa; A Inatsuki; Y Kobayashi
Journal:  J Immunol       Date:  1989-09-15       Impact factor: 5.422

3.  HLA-restricted lysis of herpes simplex virus-infected monocytes and macrophages mediated by CD4+ and CD8+ T lymphocytes.

Authors:  D J Torpey; M D Lindsley; C R Rinaldo
Journal:  J Immunol       Date:  1989-02-15       Impact factor: 5.422

4.  Behçet's disease and major histocompatibility complex class II antigens in Tunisians.

Authors:  M Hamza; K Ayed; K Hamzaoui; R Bardi
Journal:  Dis Markers       Date:  1988 Oct-Dec       Impact factor: 3.434

5.  T lymphocyte cytotoxicity with natural varicella-zoster virus infection and after immunization with live attenuated varicella vaccine.

Authors:  P S Diaz; S Smith; E Hunter; A M Arvin
Journal:  J Immunol       Date:  1989-01-15       Impact factor: 5.422

6.  Natural killer cell activity, interferon-gamma and antibodies to herpes viruses in patients with Behçet's disease.

Authors:  K Hamzaoui; K Ayed; A Slim; M Hamza; J Touraine
Journal:  Clin Exp Immunol       Date:  1990-01       Impact factor: 4.330

7.  CD4 and CD8 cell responses to herpes simplex virus in Behçet's disease.

Authors:  C Young; T Lehner; C G Barnes
Journal:  Clin Exp Immunol       Date:  1988-07       Impact factor: 4.330

8.  The human MHC-restricted cellular response to herpes simplex virus type 1 is mediated by CD4+, CD8- T cells and is restricted to the DR region of the MHC complex.

Authors:  D S Schmid
Journal:  J Immunol       Date:  1988-05-15       Impact factor: 5.422

9.  Immune responses to herpes simplex virus in patients with recurrent herpes labialis: I. Development of cell-mediated cytotoxic responses.

Authors:  H Tsutsumi; J M Bernstein; M Riepenhoff-Talty; E Cohen; F Orsini; P L Ogra
Journal:  Clin Exp Immunol       Date:  1986-12       Impact factor: 4.330

10.  Impaired measles virus-specific cytotoxic T cell responses in multiple sclerosis.

Authors:  S Jacobson; M L Flerlage; H F McFarland
Journal:  J Exp Med       Date:  1985-09-01       Impact factor: 14.307
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  7 in total

1.  Expression of Bcl-2 in inflammatory sites from patients with active Behçet's disease.

Authors:  K Hamzaoui; A Hamzaoui; L Zakraoui; A Chabbou
Journal:  Mediators Inflamm       Date:  1999       Impact factor: 4.711

2.  A rare manifestation of Behçet's syndrome: immunological correlates and successful treatment of an esophageal ulcer.

Authors:  Heiner Wedemeyer; Jens G Kuipers; Konrad Streetz; Michael Mengel; Ingolf Schedel; Nikolina Kezmic; Peter Meier; Henning Zeidler; Michael P Manns; Siegfried Wagner
Journal:  Dig Dis Sci       Date:  2003-07       Impact factor: 3.199

3.  Treatment of ocular symptoms of Behçet's disease with interferon alpha 2a: a pilot study.

Authors:  I Kötter; A K Eckstein; N Stübiger; M Zierhut
Journal:  Br J Ophthalmol       Date:  1998-05       Impact factor: 4.638

4.  Herpes simplex virus infection of human fibroblasts and keratinocytes inhibits recognition by cloned CD8+ cytotoxic T lymphocytes.

Authors:  D M Koelle; M A Tigges; R L Burke; F W Symington; S R Riddell; H Abbo; L Corey
Journal:  J Clin Invest       Date:  1993-03       Impact factor: 14.808

5.  Phenotype and functional changes of Vgamma9/Vdelta2 T lymphocytes in Behçet's disease and the effect of infliximab on Vgamma9/Vdelta2 T cell expansion, activation and cytotoxicity.

Authors:  Antonina Accardo-Palumbo; Anna Rita Giardina; Francesco Ciccia; Angelo Ferrante; Alfonso Principato; Rosalia Impastato; Ennio Giardina; Giovanni Triolo
Journal:  Arthritis Res Ther       Date:  2010-06-03       Impact factor: 5.156

6.  Interleukin-6 in peripheral blood and inflammatory sites in Behçet's disease.

Authors:  K Hamzaoui; A Hamzaoui; A Kahan; M Hamza; A Chabbou; K Ayed
Journal:  Mediators Inflamm       Date:  1992       Impact factor: 4.711

7.  Tc1/Tc2 ratio in the inflammatory process in patients with Behçet's disease.

Authors:  Habib Houman; Agnes Hamzaoui; Imed Ben Ghorbal; Monia Smiti Khanfir; Moncef Feki; Kamel Hamzaoui
Journal:  Mediators Inflamm       Date:  2004-08       Impact factor: 4.711
  7 in total

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