Literature DB >> 21688116

The importance of methylmalonic acid dosage on the assessment of patients with neurological manifestations following bariatric surgery.

Camilo Vieira1, Camila Cosmo, Rita Lucena.   

Abstract

Vitamin B12 or cyanocobalamin is an important substance that is included in several metabolic pathways. Its deficiency is a common event after bariatric surgery, decreasing the vitamin B12 absorption after almost all of the stomach and duodenum are eliminated from the digestion process. Neurological manifestations of cyanocobalamin deficiency are not uncommon. We report a case of a young woman who developed ataxia, weakness and peripheral neuropathy after bariatric surgery, but with normal value of vitamin B12 dosage. For the diagnosis, it was necessary to dose methylmalonic acid. We discuss the importance of methylmalonic acid dosage after bariatric surgery in patients who present suspect of cyanocobalamin deficiency with normal values of this vitamin and the role of proton pump inhibitor use and vitamin supplementation in patients with early neurological presentation.

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Year:  2011        PMID: 21688116     DOI: 10.1007/s11695-011-0449-3

Source DB:  PubMed          Journal:  Obes Surg        ISSN: 0960-8923            Impact factor:   4.129


  30 in total

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Journal:  J Nutr       Date:  2002-09       Impact factor: 4.798

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Journal:  Am J Clin Nutr       Date:  1995-11       Impact factor: 7.045

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Review 1.  Pharmacotherapy prevention and management of nutritional deficiencies post Roux-en-Y gastric bypass.

Authors:  Radmila Levinson; Jon B Silverman; Jennifer G Catella; Iwona Rybak; Hina Jolin; Kellene Isom
Journal:  Obes Surg       Date:  2013-07       Impact factor: 4.129

2.  Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient--2013 update: cosponsored by American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic & Bariatric Surgery.

Authors:  Jeffrey I Mechanick; Adrienne Youdim; Daniel B Jones; W Timothy Garvey; Daniel L Hurley; M Molly McMahon; Leslie J Heinberg; Robert Kushner; Ted D Adams; Scott Shikora; John B Dixon; Stacy Brethauer
Journal:  Obesity (Silver Spring)       Date:  2013-03       Impact factor: 5.002

3.  Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient--2013 update: cosponsored by American Association of Clinical Endocrinologists, the Obesity Society, and American Society for Metabolic & Bariatric Surgery.

Authors:  Jeffrey I Mechanick; Adrienne Youdim; Daniel B Jones; W Timothy Garvey; Daniel L Hurley; M Molly McMahon; Leslie J Heinberg; Robert Kushner; Ted D Adams; Scott Shikora; John B Dixon; Stacy Brethauer
Journal:  Endocr Pract       Date:  2013 Mar-Apr       Impact factor: 3.443

  3 in total

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