Literature DB >> 21686921

Scrotal carcinoma: a reminder of a disappearing occupational disease.

Sarah Saunders1, Julie Martin, Dean Harmse.   

Abstract

A 55-year-old man presented with a 12 month history of a gradually enlarging eroded lesion on his right scrotum. The patient was a 15-20 cigarettes a day lifelong smoker. Initial histological examination showed a benign squamous lesion. Repeat biopsy at 3 months now showed a poorly differentiated squamous cell carcinoma. Occupational enquiry revealed a long history of exposure to mineral oils. The carcinogenic properties of mineral oils is well recognised and is strongly linked with squamous cell carcinoma (SCC) of the skin, including scrotal carcinoma. This case report highlights the importance of reviewing histology with a second biopsy if clinical manifestations change, and secondly to obtain a thorough occupational history in oddly- presenting lesions.

Entities:  

Year:  2009        PMID: 21686921      PMCID: PMC3027920          DOI: 10.1136/bcr.06.2008.0132

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  6 in total

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Authors:  B Ramazzini
Journal:  Am J Public Health       Date:  2001-09       Impact factor: 9.308

2.  Epidemiologic estimate of the proportion of fatalities related to occupational factors in Finland.

Authors:  M Nurminen; A Karjalainen
Journal:  Scand J Work Environ Health       Date:  2001-06       Impact factor: 5.024

3.  Overall evaluations of carcinogenicity: an updating of IARC Monographs volumes 1 to 42.

Authors: 
Journal:  IARC Monogr Eval Carcinog Risks Hum Suppl       Date:  1987

4.  A brief history of scrotal cancer.

Authors:  H A Waldron
Journal:  Br J Ind Med       Date:  1983-11

Review 5.  Dying for work: The magnitude of US mortality from selected causes of death associated with occupation.

Authors:  Kyle Steenland; Carol Burnett; Nina Lalich; Elizabeth Ward; Joseph Hurrell
Journal:  Am J Ind Med       Date:  2003-05       Impact factor: 2.214

6.  Models for skin tumour risks in workers exposed to mineral oils.

Authors:  B Järvholm; D Easton
Journal:  Br J Cancer       Date:  1990-12       Impact factor: 7.640

  6 in total

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