Literature DB >> 21686891

Neuro-regression in vitamin B12 deficiency.

Sanwar Agrawal1, Shweta Nathani.   

Abstract

Neuroregression in infants has varied aetiology and vitamin B12 deficiency is one of the uncommon causes. Infantile vitamin B12 deficiency is encountered in malnourished infants or in offspring of strict vegan mothers. We present two cases, both infants of 10 and 8 months of age, whose mothers had vitamin B12 deficiency. On admission, the patients were apathic, hypotonic and lethargic. Serum vitamin B12 levels were below normal limits. On cranial MRI, T2-weighted images revealed frontoparietal cortical atrophy. Both the infants responded to vitamin B12 treatment.

Entities:  

Year:  2009        PMID: 21686891      PMCID: PMC3029636          DOI: 10.1136/bcr.06.2008.0235

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  11 in total

Review 1.  MRI of the spinal cord in myelopathy complicating vitamin B12 deficiency: two additional cases and a review of the literature.

Authors:  S S Bassi; K K Bulundwe; G P Greeff; J H Labuscagne; R F Gledhill
Journal:  Neuroradiology       Date:  1999-04       Impact factor: 2.804

2.  Involuntary movements and magnetic resonance imaging findings in infantile cobalamine (vitamin B12) deficiency.

Authors:  Zekai Avci; Tuba Turul; Sabiha Aysun; Işiil Unal
Journal:  Pediatrics       Date:  2003-09       Impact factor: 7.124

3.  Case of the season. Megaloblastic anemia with subacute combined degeneration (SCD) of the spinal cord.

Authors:  S Sharma; G C Khilnani; M Berry
Journal:  Semin Roentgenol       Date:  1999-01       Impact factor: 0.800

4.  Vitamin B12 deficiency: a cause of abnormal movements in infants.

Authors:  E S Emery; A C Homans; R B Colletti
Journal:  Pediatrics       Date:  1997-02       Impact factor: 7.124

Review 5.  Persistence of neurological damage induced by dietary vitamin B-12 deficiency in infancy.

Authors:  U von Schenck; C Bender-Götze; B Koletzko
Journal:  Arch Dis Child       Date:  1997-08       Impact factor: 3.791

6.  Retardation of myelination due to dietary vitamin B12 deficiency: cranial MRI findings.

Authors:  K Lövblad; G Ramelli; L Remonda; A C Nirkko; C Ozdoba; G Schroth
Journal:  Pediatr Radiol       Date:  1997-02

7.  Vitamin B12 deficiency in infancy as a cause of developmental regression.

Authors:  Erasmo Barbante Casella; Marcelo Valente; Jessie Medeiros de Navarro; Fernando Kok
Journal:  Brain Dev       Date:  2005-12       Impact factor: 1.961

8.  Severe vitamin B12 deficiency in an infant associated with a maternal deficiency and a strict vegetarian diet.

Authors:  Rachel Weiss; Yacov Fogelman; Michael Bennett
Journal:  J Pediatr Hematol Oncol       Date:  2004-04       Impact factor: 1.289

9.  Long-term neurologic consequences of nutritional vitamin B12 deficiency in infants.

Authors:  S M Graham; O M Arvela; G A Wise
Journal:  J Pediatr       Date:  1992-11       Impact factor: 4.406

Review 10.  Vitamin B12 metabolism and status during pregnancy, lactation and infancy.

Authors:  L H Allen
Journal:  Adv Exp Med Biol       Date:  1994       Impact factor: 2.622

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  1 in total

1.  Vitamin B12 deficiency as a cause of severe neurological symptoms in breast fed infant - a case report.

Authors:  Cezary Dubaj; Katarzyna Czyż; Wanda Furmaga-Jabłońska
Journal:  Ital J Pediatr       Date:  2020-03-30       Impact factor: 2.638

  1 in total

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