Literature DB >> 21686753

Small bowel angiodysplasia in a patient on haemodialysis: difficulties in diagnosis and management.

Smeeta Sinha1, Jessica L R Williams, Helen Eddington, Constantina Chrysochou, Elizabeth Lamerton, Christopher Babbs, Alistair Cowie, David J Smithard, Philip A Kalra.   

Abstract

Angiodysplasia is a common cause of gastrointestinal blood loss in patients with end stage renal disease. Diagnosis is especially difficult when the angiodysplastic lesions are concentrated in the small bowel. This report describes a case of a patient on haemodialysis who had transfusion-dependent anaemia from small bowel angiodysplasia. Endoscopic treatment was unsuccessful, tranexamic acid caused complications with thrombosis, and thalidomide showed no benefit. This case report highlights the problems in the diagnosis and management of this condition in patients on haemodialysis. Early diagnosis and optimisation of the patient for treatment is key to the successful outcomes of such patients.

Entities:  

Year:  2009        PMID: 21686753      PMCID: PMC3029812          DOI: 10.1136/bcr.07.2008.0542

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

1.  Impact of emergency angiography in massive lower gastrointestinal bleeding.

Authors:  W Browder; E J Cerise; M S Litwin
Journal:  Ann Surg       Date:  1986-11       Impact factor: 12.969

2.  Small bowel exploration by wireless capsule endoscopy: results from 314 procedures.

Authors:  Giacomo C Sturniolo; Vincenza Di Leo; Maria G Vettorato; Michele De Boni; Francesca Lamboglia; Manuela De Bona; Angelo Bellumat; Diego Martines; Renata D'Inca
Journal:  Am J Med       Date:  2006-04       Impact factor: 4.965

3.  Gastrointestinal bleeding in dialysis patients.

Authors:  C C Doherty
Journal:  Nephron       Date:  1993       Impact factor: 2.847

4.  A multicenter, randomized, clinical trial of hormonal therapy in the prevention of rebleeding from gastrointestinal angiodysplasia.

Authors:  F Junquera; F Feu; M Papo; S Videla; J R Armengol; J M Bordas; E Saperas; J M Piqué; J R Malagelada
Journal:  Gastroenterology       Date:  2001-11       Impact factor: 22.682

5.  Upper gastrointestinal bleeding in patients with chronic renal failure: role of vascular ectasia.

Authors:  N Chalasani; G Cotsonis; C M Wilcox
Journal:  Am J Gastroenterol       Date:  1996-11       Impact factor: 10.864

6.  Treatment of chronic transfusion-dependent gastric antral vascular ectasia (watermelon stomach) with thalidomide.

Authors:  Kathryn A Dunne; J Hill; J F Dillon
Journal:  Eur J Gastroenterol Hepatol       Date:  2006-04       Impact factor: 2.566

7.  Upper gastrointestinal bleeding in patients with chronic renal failure.

Authors:  G R Zuckerman; G L Cornette; R E Clouse; H R Harter
Journal:  Ann Intern Med       Date:  1985-05       Impact factor: 25.391

Review 8.  Double-balloon endoscopy for the diagnosis and treatment of small intestinal disease.

Authors:  H Kita; H Yamamoto
Journal:  Best Pract Res Clin Gastroenterol       Date:  2006-02       Impact factor: 3.043

9.  Tranexamic acid is beneficial as adjunctive therapy in treating major upper gastrointestinal bleeding in dialysis patients.

Authors:  Miso Sabovic; Janez Lavre; Bojan Vujkovac
Journal:  Nephrol Dial Transplant       Date:  2003-07       Impact factor: 5.992

  9 in total
  2 in total

1.  Tranexamic acid in treatment-resistant chronic transfusion-dependent gastrointestinal angiodysplasia bleeding.

Authors:  Karina V Grooteman; Erwin J M van Geenen; Joost P H Drenth
Journal:  BMJ Case Rep       Date:  2017-11-01

2.  Successful resection of complicated bleeding arteriovenous malformation of the jejunum in patients starting dual-antiplatelet therapy just after implanting a drug-eluting coronary stent.

Authors:  Takahisa Fujikawa; Hisatsugu Maekawa; Kei Shiraishi; Akira Tanaka
Journal:  BMJ Case Rep       Date:  2012-09-24
  2 in total

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