Literature DB >> 21686644

Post-mortem evidence of idiopathic left ventricular hypertrophy and idiopathic interstitial myocardial fibrosis: is exercise the cause?

Gregory Whyte1, Mary Sheppard, Keith George, Robert Shave, Sanjay Prasad, Rory O'Hanlon, Sanjay Sharma.   

Abstract

We report the case of an experienced, highly trained marathon runner who died suddenly while running. On post-mortem examination, left ventricle hypertrophy and idiopathic interstitial myocardial fibrosis was found. We believe that life-long, repetitive bouts of arduous physical activity resulted in fibrous replacement of the myocardium, causing a pathological substrate for the propagation of fatal arrhythmias.

Entities:  

Year:  2009        PMID： 21686644      PMCID： PMC3030112          DOI： 10.1136/bcr.08.2008.0758

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  11 in total

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Journal:  J Am Coll Cardiol       Date:  1996-08       Impact factor: 24.094

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Authors:  Gregory Whyte; Keith George; Robert Shave; Ellen Dawson; Claire Stephenson; Ben Edwards; David Gaze; David Oxborough; Jan Forster; Rickie Simspon
Journal:  Clin Sci (Lond)       Date:  2005-01       Impact factor: 6.124

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Authors:  M M Marijianowski; P Teeling; J Mann; A E Becker
Journal:  J Am Coll Cardiol       Date:  1995-05       Impact factor: 24.094

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Journal:  Eur Heart J       Date:  1993-11       Impact factor: 29.983

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Journal:  Cardiology       Date:  1993       Impact factor: 1.869
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  3 in total

1.  Exercise-induced arterial hypertension - an independent factor for hypertrophy and a ticking clock for cardiac fatigue or atrial fibrillation in athletes?

Authors:  Roman Leischik; Norman Spelsberg; Hiltrud Niggemann; Birgit Dworrak; Klaus Tiroch
Journal:  F1000Res       Date:  2014-05-12

2.  Histological evidence for reversible cardiomyocyte changes and serum cardiac troponin T elevation after exercise in rats.

Authors:  Jinlei Nie; Keith George; Fei Duan; Tomas K Tong; Ye Tian
Journal:  Physiol Rep       Date:  2016-12

Review 3.  Role of Cardiac Magnetic Resonance Imaging in the Evaluation of Athletes with Premature Ventricular Beats.

Authors:  Giulia Brunetti; Alberto Cipriani; Martina Perazzolo Marra; Manuel De Lazzari; Barbara Bauce; Chiara Calore; Ilaria Rigato; Francesca Graziano; Riccardo Vio; Domenico Corrado; Alessandro Zorzi
Journal:  J Clin Med       Date:  2022-01-14       Impact factor: 4.241
  3 in total

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