Literature DB >> 21686577

Benign endoscopic biopsies may be a red herring.

Laith Alrubaiy1, Waqar Ahmed, Jonathan Sutton.   

Abstract

A 64-year-old man presented with haematemesis and melena. Repeated endoscopies showed extensive candidiasis with an exophytic mass like a shelf of tumour. Biopsies showed chronic inflammatory changes with candidiasis without evidence of malignancy. His only complaint was feeling tired and loss of energy. There was no dysphagia but slight retrostenal discomfort on swallowing. Computed tomography scan reported an opacification in the right upper lobe adjacent to the mediastinum. This contained air bronchograms and several irregular air filled cavities. There was significant mediastinal adenopathy. Two endoscopies were done after that and both of them demonstrated a fistulous connection with the bronchial tree. Biopsies failed to show any neoplasm. The patient underwent a three stage oesophagectomy with removal of the adjacent lung lobe and a reconstructive procedure. The resected mass was sent for histopathology which showed a well differentiated squamous cell carcinoma of the oesophagus which locally invaded the lung.

Entities:  

Year:  2009        PMID: 21686577      PMCID: PMC3030219          DOI: 10.1136/bcr.09.2008.0894

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  13 in total

Review 1.  Long-term risk of oesophagitis, Barrett's oesophagus and oesophageal cancer in achalasia patients.

Authors:  Ivonne Leeuwenburgh; Jelle Haringsma; Herman Van Dekken; Pieter Scholten; Peter D Siersema; Ernst J Kuipers
Journal:  Scand J Gastroenterol Suppl       Date:  2006

2.  Esophagectomy for end stage achalasia.

Authors:  Stephen M Glatz; J David Richardson
Journal:  J Gastrointest Surg       Date:  2007-07-11       Impact factor: 3.452

3.  Squamous mucosal alterations in esophagectomy specimens from patients with end-stage achalasia.

Authors:  M B Lehman; S B Clark; A H Ormsby; T W Rice; J E Richter; J R Goldblum
Journal:  Am J Surg Pathol       Date:  2001-11       Impact factor: 6.394

4.  Clinicopathological studies of esophageal carcinoma in achalasia: analyses of carcinogenesis using histological and immunohistochemical procedures.

Authors:  O Chino; H Kijima; H Shimada; T Nishi; H Tanaka; G Oshiba; Y Kise; H Kajiwara; T Tsuchida; M Tanaka; T Tajima; H Makuuchi
Journal:  Anticancer Res       Date:  2000 Sep-Oct       Impact factor: 2.480

Review 5.  Pseudoachalasia: a case series and analysis of the literature.

Authors:  Ines Gockel; Volker F Eckardt; Thomas Schmitt; Theodor Junginger
Journal:  Scand J Gastroenterol       Date:  2005-04       Impact factor: 2.423

6.  The spectrum of carcinoma arising in Barrett's esophagus. A clinicopathologic study of 26 patients.

Authors:  R R Smith; S R Hamilton; J K Boitnott; E L Rogers
Journal:  Am J Surg Pathol       Date:  1984-08       Impact factor: 6.394

Review 7.  Achalasia: an overview of diagnosis and treatment.

Authors:  Daniel Pohl; Radu Tutuian
Journal:  J Gastrointestin Liver Dis       Date:  2007-09       Impact factor: 2.008

8.  Difficulties in the diagnosis of pseudoachalasia.

Authors:  J P Tracey; M Traube
Journal:  Am J Gastroenterol       Date:  1994-11       Impact factor: 10.864

9.  p53 and MIB-1 expression of esophageal carcinoma concominant with achalasia.

Authors:  Takashi Iwata; Nobuhiro Kurita; Masaki Nishioka; Hidenori Miyamoto; Shingo Wakatsuki; Toshiaki Sano; Seiki Tashiro; Mitsuo Shimada
Journal:  Hepatogastroenterology       Date:  2007 Jul-Aug

10.  Candida colonization in patients with esophageal disease: a prospective clinical study.

Authors:  L Bonavina; R Incarbone; M Reitano; A Tortorano; M Viviani; A Peracchia
Journal:  Dis Esophagus       Date:  2003       Impact factor: 3.429

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