Literature DB >> 21685147

Abortion decisions as inclusion and exclusion criteria in research involving pregnant women and fetuses.

Carson Strong1.   

Abstract

From the perspective of investigators conducting research involving pregnant women and fetuses, a woman's decision about whether to have an abortion can sometimes be relevant to the suitability of the woman and fetus as research subjects. However, prominent ethicists disagree over whether it is permissible for a woman's decision about abortion to be an inclusion or exclusion criterion for participation in research. A widely held view is that fetuses to be aborted and fetuses to be carried to term should be treated equally as research subjects. Some hold that this principle implies that a woman's decision about whether to have an abortion should not be an inclusion or exclusion criterion. This paper identifies types of research in which investigators might want to have inclusion or exclusion criteria based on decisions about abortion. It examines the arguments for and against having the woman's decision about abortion included in such criteria. It is argued that there are types of research in which such criteria are ethically permissible.

Entities:  

Mesh:

Year:  2011        PMID: 21685147      PMCID: PMC3241879          DOI: 10.1136/jme.2011.043661

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  16 in total

1.  On the scientific and ethical issues of fetal somatic gene therapy.

Authors:  C Coutelle; C Rodeck
Journal:  Gene Ther       Date:  2002-06       Impact factor: 5.250

2.  Ethics Advisory Board approves waivers for fetoscopy research.

Authors: 
Journal:  IRB       Date:  1979-04

3.  Prenatal gene tranfer: scientific, medical, and ethical issues: a report of the Recombinant DNA Advisory Committee.

Authors: 
Journal:  Hum Gene Ther       Date:  2000-05-01       Impact factor: 5.695

4.  Implications of restrictions on fetal research for biomedical advance.

Authors:  M J Mahoney
Journal:  Clin Res       Date:  1975-10

5.  Impact of public policy on the development of drugs for pregnant women and children.

Authors:  B L Mirkin
Journal:  Clin Res       Date:  1975-10

Review 6.  Gaps in knowledge in treating pregnant women.

Authors:  Donald Mattison; Anne Zajicek
Journal:  Gend Med       Date:  2006-09

7.  LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1.

Authors:  S Hacein-Bey-Abina; C Von Kalle; M Schmidt; M P McCormack; N Wulffraat; P Leboulch; A Lim; C S Osborne; R Pawliuk; E Morillon; R Sorensen; A Forster; P Fraser; J I Cohen; G de Saint Basile; I Alexander; U Wintergerst; T Frebourg; A Aurias; D Stoppa-Lyonnet; S Romana; I Radford-Weiss; F Gross; F Valensi; E Delabesse; E Macintyre; F Sigaux; J Soulier; L E Leiva; M Wissler; C Prinz; T H Rabbitts; F Le Deist; A Fischer; M Cavazzana-Calvo
Journal:  Science       Date:  2003-10-17       Impact factor: 47.728

Review 8.  Ethical considerations of fetal therapy.

Authors:  Ray Noble; Charles H Rodeck
Journal:  Best Pract Res Clin Obstet Gynaecol       Date:  2007-09-24       Impact factor: 5.237

9.  A comprehensive ethical framework for fetal research and its application to fetal surgery for spina bifida.

Authors:  Frank A Chervenak; Laurence B McCullough
Journal:  Am J Obstet Gynecol       Date:  2002-07       Impact factor: 8.661

10.  Perceptions of patients and physicians regarding phase I cancer clinical trials: implications for physician-patient communication.

Authors:  Neal J Meropol; Kevin P Weinfurt; Caroline B Burnett; Andrew Balshem; Al B Benson; Liana Castel; Sandra Corbett; Michael Diefenbach; Darrell Gaskin; Yun Li; Sharon Manne; John Marshall; Julia H Rowland; Elyse Slater; Daniel P Sulmasy; David Van Echo; Shakira Washington; Kevin A Schulman
Journal:  J Clin Oncol       Date:  2003-07-01       Impact factor: 44.544

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