| Literature DB >> 21683748 |
Veronica Yakovenko1, Elizabeth R Speidel, Clinton D Chapman, Nancy K Dess.
Abstract
The "food addiction" concept implies that proneness to drug dependence and to food dependence should covary. The latter was studied in low- (LoS) and high- (HiS) saccharin-consuming rats, who differ in drug self-administration (HiS>LoS) and withdrawal (LoS>HiS). Sugary food intake in the first 1-2 h was higher in HiS than LoS rats. Sugar intake predicted startle during abstinence only among LoS rats. These results may suggest bingeing-proneness in HiS rats and withdrawal-proneness among LoS rats. However, intake escalation and somatic withdrawal did not differ between lines. Further study with selectively bred rats, with attention to definitions and measures, is warranted.Entities:
Mesh：
Substances：
Year: 2011 PMID： 21683748 DOI： 10.1016/j.appet.2011.06.002
Source DB: PubMed Journal: Appetite ISSN： 0195-6663 Impact factor: 3.868