Literature DB >> 21683181

The differential effects of child abuse and posttraumatic stress disorder on schizotypal personality disorder.

Abigail D Powers1, Katherine M Thomas, Kerry J Ressler, Bekh Bradley.   

Abstract

OBJECTIVE: Previous findings suggest a relation between trauma exposure and risk for schizotypal personality disorder (SPD). However, the reasons for this relationship are not well understood. Some research suggests that exposure to trauma, particularly early trauma and child abuse, as well as posttraumatic stress disorder (PTSD) may play a role.
METHODS: We examined subjects (n = 541) recruited from the primary care clinics of an urban public hospital as part of an National Institute of Mental Health-funded study of trauma-related risk and resilience. We evaluated childhood abuse with the Childhood Trauma Questionnaire and the Early Trauma Inventory and SPD with the Schedule for Nonadaptive and Adaptive Personality. We assessed for lifetime PTSD using the Clinician-Administered PTSD Scale.
RESULTS: We found that of the 3 forms of abuse analyzed (emotional, physical, and sexual), only emotional abuse significantly predicted SPD (P < .001, R = 0.28) when all 3 abuse types were simultaneously entered into a regression model. Lifetime PTSD symptoms also significantly predicted SPD (P < .001, R = 0.26). Posttraumatic stress disorder was specifically predictive of 4 of the 8 SPD symptoms (P ≤ .001): excessive social anxiety, a lack of close friends or confidants, unusual perceptual experiences, and eccentric behavior or appearance. Using a Sobel test, we also found a partial mediation effect of PTSD on the relation between emotional abuse and SPD (z = 3.45, P < .001).
CONCLUSIONS: These findings point to the important influence of emotional abuse on SPD and suggest that PTSD symptoms may provide a link between damaging childhood experiences and SPD symptoms in traumatized adults.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 21683181      PMCID: PMC3122145          DOI: 10.1016/j.comppsych.2010.08.001

Source DB:  PubMed          Journal:  Compr Psychiatry        ISSN: 0010-440X            Impact factor:   3.735


  43 in total

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Review 4.  The development of a Clinician-Administered PTSD Scale.

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5.  Validity of the Childhood Trauma Questionnaire in an adolescent psychiatric population.

Authors:  D P Bernstein; T Ahluvalia; D Pogge; L Handelsman
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  1997-03       Impact factor: 8.829

Review 6.  The link between substance abuse and posttraumatic stress disorder in women. A research review.

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7.  Development and validation of a brief screening version of the Childhood Trauma Questionnaire.

Authors:  David P Bernstein; Judith A Stein; Michael D Newcomb; Edward Walker; David Pogge; Taruna Ahluvalia; John Stokes; Leonard Handelsman; Martha Medrano; David Desmond; William Zule
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8.  Initial reliability and validity of a new retrospective measure of child abuse and neglect.

Authors:  D P Bernstein; L Fink; L Handelsman; J Foote; M Lovejoy; K Wenzel; E Sapareto; J Ruggiero
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Review 9.  Relationships between trauma and psychosis: a review and integration.

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5.  Childhood trauma and schizotypy in non-clinical samples: A systematic review and meta-analysis.

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