Literature DB >> 21682742

Beyond immediate hypersensitivity: evolving roles for IgE antibodies in immune homeostasis and allergic diseases.

Oliver T Burton1, Hans C Oettgen.   

Abstract

Immunoglobulin E (IgE) antibodies have long been recognized as the antigen-specific triggers of allergic reactions. This review briefly introduces the established functions of IgE in immediate hypersensitivity and then focuses on emerging evidence from our own investigations as well as those of others that IgE plays important roles in protective immunity against parasites and exerts regulatory influences in the expression of its own receptors, FcεRI and CD23, as well as controlling mast cell homeostasis. We provide an overview of the multifaceted ways in which IgE antibodies contribute to the pathology of food allergy and speculate regarding potential mechanisms of action of IgE blockade.
© 2011 John Wiley & Sons A/S.

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Year:  2011        PMID： 21682742      PMCID： PMC3122143          DOI： 10.1111/j.1600-065X.2011.01024.x

Source DB:  PubMed          Journal:  Immunol Rev        ISSN： 0105-2896            Impact factor:   12.988


  136 in total

1.  Regulation of highly cytokinergic IgE-induced mast cell adhesion by Src, Syk, Tec, and protein kinase C family kinases.

Authors:  Jiro Kitaura; Koji Eto; Tatsuya Kinoshita; Yuko Kawakami; Michael Leitges; Clifford A Lowell; Toshiaki Kawakami
Journal:  J Immunol       Date:  2005-04-15       Impact factor: 5.422

2.  CD23-mediated IgE transport across human intestinal epithelium: inhibition by blocking sites of translation or binding.

Authors:  Yahong Tu; Sa'ad Salim; Jackie Bourgeois; Vincenza Di Leo; E Jan Irvine; John K Marshall; Mary H Perdue
Journal:  Gastroenterology       Date:  2005-09       Impact factor: 22.682

3.  IL-4-induced priming of human intestinal mast cells for enhanced survival and Th2 cytokine generation is reversible and associated with increased activity of ERK1/2 and c-Fos.

Authors:  Axel Lorentz; Mikosch Wilke; Gernot Sellge; Hans Worthmann; Jürgen Klempnauer; Michael P Manns; Stephan C Bischoff
Journal:  J Immunol       Date:  2005-06-01       Impact factor: 5.422

Review 4.  IgE: a question of protective immunity in Trichinella spiralis infection.

Authors:  Naohiro Watanabe; Fabrizio Bruschi; Masataka Korenaga
Journal:  Trends Parasitol       Date:  2005-04

5.  IgE- and IgE+Ag-mediated mast cell migration in an autocrine/paracrine fashion.

Authors:  Jiro Kitaura; Tatsuya Kinoshita; Masaaki Matsumoto; Shaun Chung; Yuko Kawakami; Michael Leitges; Dianqing Wu; Clifford A Lowell; Toshiaki Kawakami
Journal:  Blood       Date:  2005-01-06       Impact factor: 22.113

6.  IgE enhances antibody and T cell responses in vivo via CD23+ B cells.

Authors:  Andrew Getahun; Fredrik Hjelm; Birgitta Heyman
Journal:  J Immunol       Date:  2005-08-01       Impact factor: 5.422

7.  Rapid and large amount of autocrine IL-3 production is responsible for mast cell survival by IgE in the absence of antigen.

Authors:  Masayuki Kohno; Sho Yamasaki; Victor L J Tybulewicz; Takashi Saito
Journal:  Blood       Date:  2004-11-12       Impact factor: 22.113

Review 8.  Antigen-independent effects of immunoglobulin E.

Authors:  Paul J Bryce; Hans C Oettgen
Journal:  Curr Allergy Asthma Rep       Date:  2005-05       Impact factor: 4.919

9.  IgE alone promotes human lung mast cell survival through the autocrine production of IL-6.

Authors:  Glenn Cruse; Sarah Cockerill; Peter Bradding
Journal:  BMC Immunol       Date:  2008-01-23       Impact factor: 3.615

10.  IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity.

Authors:  Elizabeth E Forbes; Katherine Groschwitz; J Pablo Abonia; Eric B Brandt; Elizabeth Cohen; Carine Blanchard; Richard Ahrens; Luqman Seidu; Andrew McKenzie; Richard Strait; Fred D Finkelman; Paul S Foster; Klaus I Matthaei; Marc E Rothenberg; Simon P Hogan
Journal:  J Exp Med       Date:  2008-03-31       Impact factor: 14.307
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  49 in total

1.  [Bone marrow hematopoiesis. Evaluation of the myelogram].

Authors:  E B Vladimirskaia
Journal:  Gematol Transfuziol       Date:  1990-08       Impact factor: 0.172

Review 2.  The Immunologic Mechanisms of Eosinophilic Esophagitis.

Authors:  David A Hill; Jonathan M Spergel
Journal:  Curr Allergy Asthma Rep       Date:  2016-02       Impact factor: 4.806

3.  Allergic host defences.

Authors:  Noah W Palm; Rachel K Rosenstein; Ruslan Medzhitov
Journal:  Nature       Date:  2012-04-25       Impact factor: 49.962

4.  Immuno-evasive tactics by schistosomes identify an effective allergy preventative.

Authors:  Qyana Griffith; YanMei Liang; Patrick Whitworth; Carlos Rodriguez-Russo; Ahmad Gul; Afzal A Siddiqui; John Connor; Pauline Mwinzi; Lisa Ganley-Leal
Journal:  Exp Parasitol       Date:  2015-03-24       Impact factor: 2.011

5.  Low immunoglobulin E flags two distinct types of immune dysregulation.

Authors:  M Elkuch; V Greiff; C T Berger; M Bouchenaki; T Daikeler; A Bircher; A A Navarini; I Heijnen; M Recher
Journal:  Clin Exp Immunol       Date:  2017-01-11       Impact factor: 4.330

Review 6.  IgE receptor signaling in food allergy pathogenesis.

Authors:  Hans C Oettgen; Oliver T Burton
Journal:  Curr Opin Immunol       Date:  2015-09-18       Impact factor: 7.486

7.  Antigen-induced mast cell expansion and bronchoconstriction in a mouse model of asthma.

Authors:  Shannon Li; Minara Aliyeva; Nirav Daphtary; Rebecca A Martin; Matthew E Poynter; Shannon F Kostin; Jos L van der Velden; Alexandra M Hyman; Christopher S Stevenson; Jonathan E Phillips; Lennart K A Lundblad
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2013-11-27       Impact factor: 5.464

8.  Oral antigens induce rheumatoid arthritis-like inflammation in a rat model.

Authors:  Dandan Wu; Xiaoyu Liu; Hong Su; Xiao Chen; Huiyun Zhang; Dongsheng Hu; Zhong Huang; Ping-Chang Yang; Zhigang Liu
Journal:  Inflamm Res       Date:  2012-12-11       Impact factor: 4.575

Review 9.  Key mediators in the immunopathogenesis of allergic asthma.

Authors:  Sannette Hall; Devendra K Agrawal
Journal:  Int Immunopharmacol       Date:  2014-06-13       Impact factor: 4.932

10.  Mechanisms of vitamin D₃ metabolite repression of IgE-dependent mast cell activation.

Authors:  Kwok-Ho Yip; Natasha Kolesnikoff; Chunping Yu; Nicholas Hauschild; Houng Taing; Lisa Biggs; David Goltzman; Philip A Gregory; Paul H Anderson; Michael S Samuel; Stephen J Galli; Angel F Lopez; Michele A Grimbaldeston
Journal:  J Allergy Clin Immunol       Date:  2014-01-22       Impact factor: 10.793
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