Literature DB >> 21681360

5-year recurrence rates of Mohs micrographic surgery for aggressive and recurrent facial basal cell carcinoma.

John Paoli1, Samuel Daryoni, Ann-Marie Wennberg, Lena Mölne, Martin Gillstedt, Marinko Miocic, Bo Stenquist.   

Abstract

Mohs micrographic surgery allows for complete microscopic examination of the surgical margin when treating aggressive and recurrent facial basal cell carcinomas. This leads to the highest cure rates and maximal preservation of healthy tissue. The 5-year recurrence rates of 587 aggressive and/or recurrent facial basal cell carcinomas treated during 1993 to 2003 at our centre were studied retrospectively. The resulting 5-year recurrence rates using Kaplan-Meier survival analysis were 2.1% for primary (previously untreated) tumours, 5.2% for recurrent basal cell carcinomas and 3.3% overall. In total, 87.9% of the tumours required at least two stages of Mohs micrographic surgery. The surgical defect's size after complete excision was, on average, approximately twice the size of the defect after excision of the clinically visible tumour with a 2-3 mm margin. Mohs micro-graphic surgery is underused in Scandinavia despite being the treatment of choice for aggressive and recurrent facial basal cell carcinomas.

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Year:  2011        PMID: 21681360     DOI: 10.2340/00015555-1134

Source DB:  PubMed          Journal:  Acta Derm Venereol        ISSN: 0001-5555            Impact factor:   4.437


  10 in total

1.  Cancer worry after facial nonmelanoma skin cancer resection and reconstruction: A 1-year prospective study.

Authors:  Lucy J van Hensbergen; Inge J Veldhuizen; Erica H Lee; Saskia Houterman; Tjinta Brinkhuizen; René R W J van der Hulst; Maarten M Hoogbergen
Journal:  Psychooncology       Date:  2021-09-14       Impact factor: 3.955

2.  Mohs micrographic surgery for periocular skin tumours in Ireland.

Authors:  M P Treacy; N C Wynne; J L Gale; E Duignan; B Moran; A M Flynn; P Ormond; R Barry; R Khan; P Moriarty; L Cassidy
Journal:  Ir J Med Sci       Date:  2015-07-11       Impact factor: 1.568

3.  The value of mohs surgery for the treatment of nonmelanoma skin cancers.

Authors:  Joseph Alcalay
Journal:  J Cutan Aesthet Surg       Date:  2012-01

4.  Nonmelanoma skin cancer.

Authors:  Venura Samarasinghe; Vishal Madan
Journal:  J Cutan Aesthet Surg       Date:  2012-01

5.  Cryosurgery of Periocular Moderately Aggressive Basal Cell Carcinoma.

Authors:  Oscar Finskas; Oscar Zaar; Karin Svedberg
Journal:  Acta Derm Venereol       Date:  2020-11-26       Impact factor: 3.875

Review 6.  [Basal cell basal cell epithelioma of the face: surgical management, about 45 cases and review of the literature].

Authors:  Mohamed Amine Ennouhi; Abdenacer Moussaoui
Journal:  Pan Afr Med J       Date:  2014-09-25

7.  Combining three-dimensional histopathology with bread loafing and orientation without artificial coloring.

Authors:  Nina Zila; Philipp Tschandl
Journal:  J Cutan Pathol       Date:  2022-04-27       Impact factor: 1.458

8.  Clinicopathological Factors Associated with Incomplete Excision of High-risk Basal Cell Carcinoma.

Authors:  Hannah Ceder; Annie Ekström; Lajla Hadzic; John Paoli
Journal:  Acta Derm Venereol       Date:  2021-07-13       Impact factor: 3.875

9.  Mohs Micrographic Surgery for Primary Versus Recurrent or Incompletely Excised Facial High-risk Basal Cell Carcinomas.

Authors:  Hannah Ceder; Malin Grönberg; John Paoli
Journal:  Acta Derm Venereol       Date:  2021-02-02       Impact factor: 3.875

10.  Basal cell carcinoma: 10-year experience with electrochemotherapy.

Authors:  Luca G Campana; Roberto Marconato; Sara Valpione; Sara Galuppo; Mauro Alaibac; Carlo R Rossi; Simone Mocellin
Journal:  J Transl Med       Date:  2017-05-31       Impact factor: 5.531

  10 in total

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