Literature DB >> 21680664

Field evaluation of five rapid diagnostic tests for screening of HIV-1 infections in rural Rakai, Uganda.

S C Kagulire1, P Opendi, P D Stamper, J L Nakavuma, L A Mills, F Makumbi, R H Gray, J P Shott, D Serwadda, S J Reynolds.   

Abstract

The performance characteristics of HIV rapid diagnostic tests (RDTs) vary by test and by population. We assessed five commercial RDTs in Uganda where all but one RDT (Determine; Abbott Laboratories, Germany) performed close to manufacturer's expectations. Determine had low specificity (85.2%, positive predictive value 67.3%) due to false-positive results with weak-positive bands. Properly trained staff, good quality control programmes and validation of RDTs with laboratories having confirmatory testing capacity may be warranted to assure accuracy in each setting.

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Year:  2011        PMID: 21680664      PMCID: PMC3726838          DOI: 10.1258/ijsa.2009.009352

Source DB:  PubMed          Journal:  Int J STD AIDS        ISSN: 0956-4624            Impact factor:   1.359


  5 in total

1.  Evaluation of rapid tests for anti-HIV detection in Brazil.

Authors:  Orlando C Ferreira Junior; Cristine Ferreira; Maristela Riedel; Marcya Regina Visinoni Widolin; Aristides Barbosa-Júnior
Journal:  AIDS       Date:  2005-10       Impact factor: 4.177

2.  Limitations of rapid HIV-1 tests during screening for trials in Uganda: diagnostic test accuracy study.

Authors:  Ronald H Gray; Fredrick Makumbi; David Serwadda; Tom Lutalo; Fred Nalugoda; Pius Opendi; Godfrey Kigozi; Steven J Reynolds; Nelson K Sewankambo; Maria J Wawer
Journal:  BMJ       Date:  2007-06-01

3.  Evaluation of Determine HIV-1/2 rapid diagnostic test by 4th generation ELISA using blood donors' serum at Felege Hiwot Referral Hospital, northwest Ethiopia.

Authors:  Azene Dessie; Bayeh Abera; Fisseha Walle; Dawit Wolday; Wogenie Tamene
Journal:  Ethiop Med J       Date:  2008-01

4.  Large-scale human immunodeficiency virus rapid test evaluation in a low-prevalence ugandan blood bank population.

Authors:  Leigh A Eller; Michael A Eller; Benson J Ouma; Peter Kataaha; Bernard S Bagaya; Robert L Olemukan; Simon Erima; Lilian Kawala; Mark S de Souza; Hannah Kibuuka; Fred Wabwire-Mangen; Sheila A Peel; Robert J O'Connell; Merlin L Robb; Nelson L Michael
Journal:  J Clin Microbiol       Date:  2007-08-15       Impact factor: 5.948

5.  The evaluation of a rapid in situ HIV confirmation test in a programme with a high failure rate of the WHO HIV two-test diagnostic algorithm.

Authors:  Derryck B Klarkowski; Joseph M Wazome; Kamalini M Lokuge; Leslie Shanks; Clair F Mills; Daniel P O'Brien
Journal:  PLoS One       Date:  2009-02-06       Impact factor: 3.240

  5 in total
  23 in total

1.  Field Evaluation of a Dual Rapid Immunodiagnostic Test for HIV and Syphilis Infection in Peru.

Authors:  Claire C Bristow; Segundo R Leon; Emily Huang; Lourdes B Ramos; Silver K Vargas; Juan A Flores; Kelika A Konda; Carlos F Caceres; Jeffrey D Klausner
Journal:  Sex Transm Dis       Date:  2016-01       Impact factor: 2.830

2.  Rapid infectious diseases diagnostics using Smartphones.

Authors:  Matthew Bates; Alimuddin Zumla
Journal:  Ann Transl Med       Date:  2015-09

3.  Evaluation of current rapid HIV test algorithms in Rakai, Uganda.

Authors:  Ronald M Galiwango; Richard Musoke; Lawrence Lubyayi; Robert Ssekubugu; Sarah Kalibbala; Viola Ssekweyama; Viola Mirembe; Gertrude Nakigozi; Steven J Reynolds; David Serwadda; Ronald H Gray; Godfrey Kigozi
Journal:  J Virol Methods       Date:  2013-04-11       Impact factor: 2.014

4.  Field evaluation of a dual rapid diagnostic test for HIV infection and syphilis in Lima, Peru.

Authors:  Claire C Bristow; Segundo R Leon; Emily Huang; Brandon J Brown; Lourdes B Ramos; Silver K Vargas; Juan A Flores; Carlos F Caceres; Jeffrey D Klausner
Journal:  Sex Transm Infect       Date:  2015-12-15       Impact factor: 3.519

Review 5.  Universal testing and treatment as an HIV prevention strategy: research questions and methods.

Authors:  Richard Hayes; Kalpana Sabapathy; Sarah Fidler
Journal:  Curr HIV Res       Date:  2011-09       Impact factor: 1.581

6.  A Quality Management Approach to Implementing Point-of-Care Technologies for HIV Diagnosis and Monitoring in Sub-Saharan Africa.

Authors:  Joseph P Shott; Ronald M Galiwango; Steven J Reynolds
Journal:  J Trop Med       Date:  2012-01-11

7.  Evaluation of Performance of Two Rapid Tests for Detection of HIV-1 and -2 in High- and Low-Prevalence Populations in Nigeria.

Authors:  Mark M Manak; Ogbonnaya S Njoku; Ashley Shutt; Jennifer Malia; Linda L Jagodzinski; Mark Milazzo; Aminu Suleiman; Amos A Ogundeji; Robert Nelson; Ojor R Ayemoba; Robert J O'Connell; Darrell E Singer; Nelson L Michael; Sheila A Peel
Journal:  J Clin Microbiol       Date:  2015-08-26       Impact factor: 5.948

Review 8.  Rapid Point-of-Care Testing for Detection of HIV and Clinical Monitoring.

Authors:  D R Arora; Megha Maheshwari; B Arora
Journal:  ISRN AIDS       Date:  2013-05-23

9.  False positive HIV diagnoses in resource limited settings: operational lessons learned for HIV programmes.

Authors:  Leslie Shanks; Derryck Klarkowski; Daniel P O'Brien
Journal:  PLoS One       Date:  2013-03-20       Impact factor: 3.240

10.  Evaluation of HIV testing algorithms in Ethiopia: the role of the tie-breaker algorithm and weakly reacting test lines in contributing to a high rate of false positive HIV diagnoses.

Authors:  Leslie Shanks; M Ruby Siddiqui; Jarmila Kliescikova; Neil Pearce; Cono Ariti; Libsework Muluneh; Erwan Pirou; Koert Ritmeijer; Johnson Masiga; Almaz Abebe
Journal:  BMC Infect Dis       Date:  2015-02-03       Impact factor: 3.090

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