BACKGROUND: We assessed whether glycated albumin (GA) is a useful glycemic indicator in diabetic patients with anemia who did not undergo dialysis. METHODS: Hemoglobin A(1c) (HbA(1c)) and GA were simultaneously measured in 370 diabetic subjects who had not undergone dialysis. The relationship between GA and HbA(1c) was evaluated in patients with and without anemia. RESULTS: GA-to-HbA(1c) ratio was significantly higher (3.3±0.7 vs. 2.8±0.5, p<0.001) and the regression slope between GA and HbA(1c) was steeper in diabetic patients with than in those without anemia (6.2 vs. 4.2, p<0.001). CONCLUSIONS: HbA(1c) was underestimated in diabetic patients with anemia than in those without anemia, with the degree of underestimation increasing as glycemic control became poorer. GA may more accurately assess glycemic control in diabetic patients with anemia than HbA(1c).
BACKGROUND: We assessed whether glycated albumin (GA) is a useful glycemic indicator in diabeticpatients with anemia who did not undergo dialysis. METHODS: Hemoglobin A(1c) (HbA(1c)) and GA were simultaneously measured in 370 diabetic subjects who had not undergone dialysis. The relationship between GA and HbA(1c) was evaluated in patients with and without anemia. RESULTS: GA-to-HbA(1c) ratio was significantly higher (3.3±0.7 vs. 2.8±0.5, p<0.001) and the regression slope between GA and HbA(1c) was steeper in diabeticpatients with than in those without anemia (6.2 vs. 4.2, p<0.001). CONCLUSIONS: HbA(1c) was underestimated in diabeticpatients with anemia than in those without anemia, with the degree of underestimation increasing as glycemic control became poorer. GA may more accurately assess glycemic control in diabeticpatients with anemia than HbA(1c).
Authors: Ledibabari M Ngaage; Emmanuel N Osadebey; Sebastian T E Tullie; Adekunle Elegbede; Erin M Rada; Elias K Spanakis; Nelson Goldberg; Sheri Slezak; Yvonne M Rasko Journal: Plast Reconstr Surg Glob Open Date: 2019-05-16
Authors: Tariq Shafi; Stephen M Sozio; Laura C Plantinga; Bernard G Jaar; Edward T Kim; Rulan S Parekh; Michael W Steffes; Neil R Powe; Josef Coresh; Elizabeth Selvin Journal: Diabetes Care Date: 2012-12-18 Impact factor: 19.112