OBJECTIVE: To determine the validity and reliability of a novel questionnaire to measure vision-related quality of life (VRQOL) in children ages 8-18 years for use in juvenile idiopathic arthritis (JIA)-associated uveitis: the Effects of Youngsters' Eyesight on Quality of Life (EYE-Q). METHODS: Several steps validated the EYE-Q. We interviewed experts and children on how vision affects a child's activities. We developed new items and selected relevant items from existing instruments. We administered initial versions of the EYE-Q to normal-sighted children and those with JIA-associated uveitis. For this study, children with various (or no) ocular conditions were recruited from a clinical population. Visual acuity and contrast sensitivity were performed, and the EYE-Q and Pediatric Quality of Life Inventory (PedsQL) were administered. The EYE-Q was repeated 10 days later. Patients, parents, and physicians rated vision severity. RESULTS: Of 120 patients, 48% were female, 46.7% had no visual impairment, and 53.3% had bilateral eye involvement. The mean age was 11.3 years. There were significant differences in the measures based on visual acuity (P < 0.001). Children with more severe visual acuity and bilateral eye involvement had worse EYE-Q scores (P < 0.001). There were significant associations between the EYE-Q and PedsQL (r = 0.375), repeat EYE-Q (r = 0.864), and clinical measures of ocular disease (r = -0.620). CONCLUSIONS: Our study provides evidence of the validity and reliability of the EYE-Q in the measurement of VRQOL. The EYE-Q may complement clinical measures of visual impairment and overall QOL and become an important tool in the assessment of QOL in JIA-associated uveitis.
OBJECTIVE: To determine the validity and reliability of a novel questionnaire to measure vision-related quality of life (VRQOL) in children ages 8-18 years for use in juvenile idiopathic arthritis (JIA)-associated uveitis: the Effects of Youngsters' Eyesight on Quality of Life (EYE-Q). METHODS: Several steps validated the EYE-Q. We interviewed experts and children on how vision affects a child's activities. We developed new items and selected relevant items from existing instruments. We administered initial versions of the EYE-Q to normal-sighted children and those with JIA-associated uveitis. For this study, children with various (or no) ocular conditions were recruited from a clinical population. Visual acuity and contrast sensitivity were performed, and the EYE-Q and Pediatric Quality of Life Inventory (PedsQL) were administered. The EYE-Q was repeated 10 days later. Patients, parents, and physicians rated vision severity. RESULTS: Of 120 patients, 48% were female, 46.7% had no visual impairment, and 53.3% had bilateral eye involvement. The mean age was 11.3 years. There were significant differences in the measures based on visual acuity (P < 0.001). Children with more severe visual acuity and bilateral eye involvement had worse EYE-Q scores (P < 0.001). There were significant associations between the EYE-Q and PedsQL (r = 0.375), repeat EYE-Q (r = 0.864), and clinical measures of ocular disease (r = -0.620). CONCLUSIONS: Our study provides evidence of the validity and reliability of the EYE-Q in the measurement of VRQOL. The EYE-Q may complement clinical measures of visual impairment and overall QOL and become an important tool in the assessment of QOL in JIA-associated uveitis.
Authors: R Gutiérrez-Suárez; A Pistorio; A Cespedes Cruz; X Norambuena; B Flato; I Rumba; M Harjacek; S Nielsen; G Susic; D Mihaylova; C Huemer; J Melo-Gomes; B Andersson-Gare; Z Balogh; C De Cunto; R Vesely; K Pagava; A M Romicka; R Burgos-Vargas; A Martini; N Ruperto Journal: Rheumatology (Oxford) Date: 2006-07-28 Impact factor: 7.580
Authors: Sheila T Angeles-Han; Kenneth W Griffin; Thomas J A Lehman; John R Rutledge; Stephen Lyman; Joseph T Nguyen; Melanie J Harrison Journal: J AAPOS Date: 2010-03-17 Impact factor: 1.220
Authors: Joost Felius; David R Stager; Priscilla M Berry; Sherry L Fawcett; David R Stager; Solange R Salomão; Adriana Berezovsky; Eileen E Birch Journal: Am J Ophthalmol Date: 2004-09 Impact factor: 5.258
Authors: Sheila T Angeles-Han; Steven Yeh; Courtney McCracken; Kirsten Jenkins; Daneka Stryker; Erica Myoung; Larry B Vogler; Kelly Rouster-Stevens; Scott R Lambert; Melanie J Harrison; Sampath Prahalad; Carolyn Drews-Botsch Journal: Arthritis Care Res (Hoboken) Date: 2015-11 Impact factor: 4.794
Authors: Sarah R Hatt; David A Leske; Yolanda S Castañeda; Suzanne M Wernimont; Laura Liebermann; Christina S Cheng-Patel; Eileen E Birch; Jonathan M Holmes Journal: Am J Ophthalmol Date: 2019-01-14 Impact factor: 5.258