Literature DB >> 21678541

An MD2 hot-spot-mimicking peptide that suppresses TLR4-mediated inflammatory response in vitro and in vivo.

Liping Liu1, Nilanjan Ghosh, Peter F Slivka, Zeno Fiorini, Mark R Hutchinson, Linda R Watkins, Hang Yin.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21678541      PMCID： PMC3374877          DOI： 10.1002/cbic.201100211

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


× No keyword cloud information.
  18 in total

1.  Glia. Glee for glia. Introduction.

Authors:  Peter Stern
Journal:  Science       Date:  2010-11-05       Impact factor: 47.728

Review 2.  Toll-like receptors in innate immunity.

Authors:  Kiyoshi Takeda; Shizuo Akira
Journal:  Int Immunol       Date:  2005-01       Impact factor: 4.823

3.  Scalable molecular dynamics with NAMD.

Authors:  James C Phillips; Rosemary Braun; Wei Wang; James Gumbart; Emad Tajkhorshid; Elizabeth Villa; Christophe Chipot; Robert D Skeel; Laxmikant Kalé; Klaus Schulten
Journal:  J Comput Chem       Date:  2005-12       Impact factor: 3.376

4.  Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.

Authors:  Alberto Visintin; Kristen A Halmen; Eicke Latz; Brian G Monks; Douglas T Golenbock
Journal:  J Immunol       Date:  2005-11-15       Impact factor: 5.422

5.  The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy.

Authors:  Flobert Y Tanga; Nancy Nutile-McMenemy; Joyce A DeLeo
Journal:  Proc Natl Acad Sci U S A       Date:  2005-04-04       Impact factor: 11.205

6.  A coiled-coil enabled split-luciferase three-hybrid system: applied toward profiling inhibitors of protein kinases.

Authors:  Benjamin W Jester; Kurt J Cox; Alicia Gaj; Carolyn D Shomin; Jason R Porter; Indraneel Ghosh
Journal:  J Am Chem Soc       Date:  2010-08-25       Impact factor: 15.419

7.  A peptide antagonist of the TLR4-MD2 interaction.

Authors:  Peter F Slivka; Mitesh Shridhar; Gui-in Lee; Deanne W Sammond; Mark R Hutchinson; Alexander J Martinko; Madison M Buchanan; Page W Sholar; Jeffrey J Kearney; Jacqueline A Harrison; Linda R Watkins; Hang Yin
Journal:  Chembiochem       Date:  2009-03-02       Impact factor: 3.164

Review 8.  Toll-like receptors expression and signaling in glia cells in neuro-amyloidogenic diseases: towards future therapeutic application.

Authors:  Dorit Trudler; Dorit Farfara; Dan Frenkel
Journal:  Mediators Inflamm       Date:  2010-07-25       Impact factor: 4.711

9.  TAK-242 selectively suppresses Toll-like receptor 4-signaling mediated by the intracellular domain.

Authors:  Tomohiro Kawamoto; Masayuki Ii; Tomoyuki Kitazaki; Yuji Iizawa; Hiroyuki Kimura
Journal:  Eur J Pharmacol       Date:  2008-02-05       Impact factor: 4.432

Review 10.  Pathological and protective roles of glia in chronic pain.

Authors:  Erin D Milligan; Linda R Watkins
Journal:  Nat Rev Neurosci       Date:  2009-01       Impact factor: 34.870
View more
  7 in total

Review 1.  Targeting protein-protein interfaces using macrocyclic peptides.

Authors:  Meng Gao; Kui Cheng; Hang Yin
Journal:  Biopolymers       Date:  2015-07       Impact factor: 2.505

2.  Morphine activates neuroinflammation in a manner parallel to endotoxin.

Authors:  Xiaohui Wang; Lisa C Loram; Khara Ramos; Armando J de Jesus; Jacob Thomas; Kui Cheng; Anireddy Reddy; Andrew A Somogyi; Mark R Hutchinson; Linda R Watkins; Hang Yin
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-02       Impact factor: 11.205

Review 3.  Therapeutic Developments Targeting Toll-like Receptor-4-Mediated Neuroinflammation.

Authors:  Jing Li; Adam Csakai; Jialin Jin; Fengchun Zhang; Hang Yin
Journal:  ChemMedChem       Date:  2015-07-01       Impact factor: 3.466

Review 4.  Targeting Toll-like receptors with small molecule agents.

Authors:  Xiaohui Wang; Christina Smith; Hang Yin
Journal:  Chem Soc Rev       Date:  2013-06-21       Impact factor: 54.564

5.  Identification of substituted pyrimido[5,4-b]indoles as selective Toll-like receptor 4 ligands.

Authors:  Michael Chan; Tomoko Hayashi; Richard D Mathewson; Afshin Nour; Yuki Hayashi; Shiyin Yao; Rommel I Tawatao; Brian Crain; Igor F Tsigelny; Valentina L Kouznetsova; Karen Messer; Minya Pu; Maripat Corr; Dennis A Carson; Howard B Cottam
Journal:  J Med Chem       Date:  2013-05-24       Impact factor: 7.446

6.  Structure-based rational design of a Toll-like receptor 4 (TLR4) decoy receptor with high binding affinity for a target protein.

Authors:  Jieun Han; Hyun Jung Kim; Sang-Chul Lee; Seungpyo Hong; Keunwan Park; Young Ho Jeon; Dongsup Kim; Hae-Kap Cheong; Hak-Sung Kim
Journal:  PLoS One       Date:  2012-02-17       Impact factor: 3.240

7.  Computational-Driven Epitope Verification and Affinity Maturation of TLR4-Targeting Antibodies.

Authors:  Bilal Ahmad; Maria Batool; Moon-Suk Kim; Sangdun Choi
Journal:  Int J Mol Sci       Date:  2021-06-01       Impact factor: 5.923
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.