Elchanan Fried1, Charles Weissman, Charles Sprung. 1. Department of Internal Medicine and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel. elchananf@hadassah.org.il
Abstract
PURPOSE OF REVIEW: Postoperative sepsis is a major cause of surgical associated morbidity and mortality. Our goal is to describe its incidence, pathophysiology, and contributing factors. In addition, we will review preventive measures and treatment options that may possibly reduce its healthcare burden. RECENT FINDINGS: We review epidemiologic data and clinical tools presented in multiple current studies, which may help lower incidence and improve outcome of postoperative sepsis. SUMMARY: The incidence of postoperative sepsis has not declined over the past years, although mortality is trending downwards. Several biochemical and genetic markers may allow early diagnosis. Prevention and prompt treatment may lower mortality.
PURPOSE OF REVIEW: Postoperative sepsis is a major cause of surgical associated morbidity and mortality. Our goal is to describe its incidence, pathophysiology, and contributing factors. In addition, we will review preventive measures and treatment options that may possibly reduce its healthcare burden. RECENT FINDINGS: We review epidemiologic data and clinical tools presented in multiple current studies, which may help lower incidence and improve outcome of postoperative sepsis. SUMMARY: The incidence of postoperative sepsis has not declined over the past years, although mortality is trending downwards. Several biochemical and genetic markers may allow early diagnosis. Prevention and prompt treatment may lower mortality.
Authors: Abdul Khairul Rizki Purba; Christian F Luz; Riyanti R Wulandari; Ieneke van der Gun; Jan-Willem Dik; Alex W Friedrich; Maarten J Postma Journal: Infect Drug Resist Date: 2020-09-30 Impact factor: 4.003
Authors: Corinne Bunn; Sujay Kulshrestha; Jason Boyda; Neelam Balasubramanian; Steven Birch; Ibrahim Karabayir; Marshall Baker; Fred Luchette; François Modave; Oguz Akbilgic Journal: Surgery Date: 2020-09-18 Impact factor: 3.982