Literature DB >> 21677254

Elevated plasma ceramides in depression.

Patricia Gracia-Garcia1, Vani Rao, Norman J Haughey, Veera Venkata Ratnam Bandaru, Veera Venkata Ratnam Banduru, Gwenn Smith, Paul B Rosenberg, Antonio Lobo, Constantine G Lyketsos, Michelle M Mielke.   

Abstract

The authors did a preliminary examination asking whether plasma ceramides were elevated in depression, and whether the elevation was more pronounced in Alzheimer's disease patients than in control subjects. Results suggest that plasma ceramides are elevated in persons with a diagnosis of major depression, regardless of dementia status.

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Year:  2011        PMID： 21677254      PMCID： PMC3121176          DOI： 10.1176/jnp.23.2.jnp215

Source DB:  PubMed          Journal:  J Neuropsychiatry Clin Neurosci        ISSN： 0895-0172            Impact factor:   2.198


  15 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-15       Impact factor: 11.205

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Authors:  J J Schildkraut
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Authors:  J C Morris
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4.  High activity of acid sphingomyelinase in major depression.

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5.  Mental and behavioral disturbances in dementia: findings from the Cache County Study on Memory in Aging.

Authors:  C G Lyketsos; M Steinberg; J T Tschanz; M C Norton; D C Steffens; J C Breitner
Journal:  Am J Psychiatry       Date:  2000-05       Impact factor: 18.112

6.  Elevated PLA2 activity in schizophrenics and other psychiatric patients.

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8.  Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease.

Authors:  G McKhann; D Drachman; M Folstein; R Katzman; D Price; E M Stadlan
Journal:  Neurology       Date:  1984-07       Impact factor: 9.910

9.  Ceramide-induced alterations in dopamine transporter function.

Authors:  Evan L Riddle; Kristi S Rau; Matthew K Topham; Glen R Hanson; Annette E Fleckenstein
Journal:  Eur J Pharmacol       Date:  2003-01-01       Impact factor: 4.432

10.  Ceramide stabilizes beta-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid beta-peptide biogenesis.

Authors:  Luigi Puglielli; Blake C Ellis; Aleister J Saunders; Dora M Kovacs
Journal:  J Biol Chem       Date:  2003-03-20       Impact factor: 5.486
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  29 in total

1.  A Lipidomics Approach to Assess the Association Between Plasma Sphingolipids and Verbal Memory Performance in Coronary Artery Disease Patients Undertaking Cardiac Rehabilitation: A C18:0 Signature for Cognitive Response to Exercise.

Authors:  Mahwesh Saleem; Nathan Herrmann; Adam Dinoff; Michelle M Mielke; Paul I Oh; Prathiba Shammi; Xingshan Cao; Swarajya Lakshmi Vattem Venkata; Norman J Haughey; Krista L Lanctôt
Journal:  J Alzheimers Dis       Date:  2017       Impact factor: 4.472

2.  Harnessing the power of yeast to elucidate the role of sphingolipids in metabolic and signaling processes pertinent to psychiatric disorders.

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Journal:  Clin Lipidol       Date:  2014-11-01

3.  Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects.

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Journal:  Psychopharmacology (Berl)       Date:  2018-08-16       Impact factor: 4.530

4.  High-Fat Diet and Short-Term Unpredictable Stress Increase Long-Chain Ceramides Without Enhancing Behavioral Despair.

Authors:  Lubriel Sambolín-Escobales; Lizmarie Tirado-Castro; Cristina Suarez; Dariangelly Pacheco-Cruz; Wilfred Fonseca-Ferrer; Pragney Deme; Norman Haughey; Gladys Chompre; James T Porter
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5.  Plasma metabolomic profiles associated with chronic distress in women.

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6.  Multivariate analysis reveals genetic associations of the resting default mode network in psychotic bipolar disorder and schizophrenia.

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7.  Plasma ceramide and glucosylceramide metabolism is altered in sporadic Parkinson's disease and associated with cognitive impairment: a pilot study.

Authors:  Michelle M Mielke; Walter Maetzler; Norman J Haughey; Veera V R Bandaru; Rodolfo Savica; Christian Deuschle; Thomas Gasser; Ann-Kathrin Hauser; Susanne Gräber-Sultan; Erwin Schleicher; Daniela Berg; Inga Liepelt-Scarfone
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8.  Shorter Chain Triglycerides Are Negatively Associated with Symptom Improvement in Schizophrenia.

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9.  Effects of Aerobic Exercise Training on Systemic Biomarkers and Cognition in Late Middle-Aged Adults at Risk for Alzheimer's Disease.

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10.  mRNA Expression of SMPD1 Encoding Acid Sphingomyelinase Decreases upon Antidepressant Treatment.

Authors:  Cosima Rhein; Iulia Zoicas; Lena M Marx; Stefanie Zeitler; Tobias Hepp; Claudia von Zimmermann; Christiane Mühle; Tanja Richter-Schmidinger; Bernd Lenz; Yesim Erim; Martin Reichel; Erich Gulbins; Johannes Kornhuber
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