Literature DB >> 21676644

Falls in Parkinson's disease: evidence for altered stepping strategies on compliant surfaces.

Michael H Cole1, Peter A Silburn, Joanne M Wood, Graham K Kerr.   

Abstract

BACKGROUND: Real-world environments comprise surfaces of different textures, densities and gradients, which can threaten postural stability and increase falls risk. However, there has been limited research that has examined how walking on compliant surfaces influences gait and postural stability in older people and PD patients.
METHODS: PD patients (n = 49) and age-matched controls (n = 32) were assessed using three-dimensional motion analysis during self-paced walking on both firm and foam walkways. Falls were recorded prospectively over 12 months using daily falls calendars.
RESULTS: Walking on a foam surface influenced the temporospatial characteristics for all groups, but PD fallers adopted very different joint kinematics compared with controls. PD fallers also demonstrated reduced toe clearance and had increased mediolateral head motion (relative to walking velocity) compared with control participants.
CONCLUSIONS: Postural control deficits in PD fallers may impair their capacity to attenuate surface-related perturbations and control head motion. The risk of falling for PD patients may be increased on less stable surfaces.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21676644     DOI: 10.1016/j.parkreldis.2011.05.019

Source DB:  PubMed          Journal:  Parkinsonism Relat Disord        ISSN: 1353-8020            Impact factor:   4.891


  10 in total

1.  Complex Movement Control in a Rat Model of Parkinsonian Falls: Bidirectional Control by Striatal Cholinergic Interneurons.

Authors:  Cassandra Avila; Aaron Kucinski; Martin Sarter
Journal:  J Neurosci       Date:  2020-06-18       Impact factor: 6.167

2.  Modeling falls in Parkinson's disease: Slow gait, freezing episodes and falls in rats with extensive striatal dopamine loss.

Authors:  Aaron Kucinski; Roger L Albin; Cindy Lustig; Martin Sarter
Journal:  Behav Brain Res       Date:  2015-01-14       Impact factor: 3.332

3.  Co-treatment with rivastigmine and idalopirdine reduces the propensity for falls in a rat model of falls in Parkinson's disease.

Authors:  Ajeesh Koshy Cherian; Aaron Kucinski; Ryan Wu; Inge E M de Jong; Martin Sarter
Journal:  Psychopharmacology (Berl)       Date:  2019-01-04       Impact factor: 4.530

Review 4.  Where attention falls: Increased risk of falls from the converging impact of cortical cholinergic and midbrain dopamine loss on striatal function.

Authors:  Martin Sarter; Roger L Albin; Aaron Kucinski; Cindy Lustig
Journal:  Exp Neurol       Date:  2014-05-05       Impact factor: 5.330

Review 5.  Wearable sensor use for assessing standing balance and walking stability in people with Parkinson's disease: a systematic review.

Authors:  Ryan P Hubble; Geraldine A Naughton; Peter A Silburn; Michael H Cole
Journal:  PLoS One       Date:  2015-04-20       Impact factor: 3.240

6.  Concurrent validity of accelerations measured using a tri-axial inertial measurement unit while walking on firm, compliant and uneven surfaces.

Authors:  Michael H Cole; Wolbert van den Hoorn; Justin K Kavanagh; Steven Morrison; Paul W Hodges; James E Smeathers; Graham K Kerr
Journal:  PLoS One       Date:  2014-05-27       Impact factor: 3.240

7.  Trunk muscle exercises as a means of improving postural stability in people with Parkinson's disease: a protocol for a randomised controlled trial.

Authors:  Ryan P Hubble; Geraldine A Naughton; Peter A Silburn; Michael H Cole
Journal:  BMJ Open       Date:  2014-12-31       Impact factor: 2.692

8.  Reduction of falls in a rat model of PD falls by the M1 PAM TAK-071.

Authors:  Aaron Kucinski; Martin Sarter
Journal:  Psychopharmacology (Berl)       Date:  2021-03-18       Impact factor: 4.415

Review 9.  Make a Left Turn: Cortico-Striatal Circuitry Mediating the Attentional Control of Complex Movements.

Authors:  Martin Sarter; Cassandra Avila; Aaron Kucinski; Eryn Donovan
Journal:  Mov Disord       Date:  2021-02-22       Impact factor: 10.338

10.  Assessment of the Kinematic Adaptations in Parkinson's Disease Using the Gait Profile Score: Influences of Trunk Posture, a Pilot Study.

Authors:  Tauana Callais Franco do Nascimento; Flavia Martins Gervásio; Antonia Pignolo; Guilherme Augusto Santos Bueno; Aline Araújo do Carmo; Darlan Martins Ribeiro; Marco D'Amelio; Felipe Augusto Dos Santos Mendes
Journal:  Brain Sci       Date:  2021-12-03
  10 in total

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