OBJECTIVES: Severely disturbed sleep is known to occur during and shortly prior to the onset of mood episodes in bipolar disorder. Whether alterations in sleep occur parallel and as part of the disease process or whether they represent a trait existent before the onset of the disorder itself remains unclear. METHODS: A systematic review evaluating all published data on the occurrence of disordered sleep prior to the onset of the first mood episode was conducted. RESULTS: The evidence cited within this paper suggests that sleep disturbances frequently precede bipolar disorder by several years and convey an elevated long-term risk for developing any kind of mood disorder. Disordered sleep appears to emerge about the time of puberty and remains persistently elevated in individuals at high risk. CONCLUSION: Disturbed sleep appears to be an early symptom of bipolar disorder but further research, especially longitudinal studies in individuals at high risk, will be required to characterize the type and patterns more precisely.
OBJECTIVES: Severely disturbed sleep is known to occur during and shortly prior to the onset of mood episodes in bipolar disorder. Whether alterations in sleep occur parallel and as part of the disease process or whether they represent a trait existent before the onset of the disorder itself remains unclear. METHODS: A systematic review evaluating all published data on the occurrence of disordered sleep prior to the onset of the first mood episode was conducted. RESULTS: The evidence cited within this paper suggests that sleep disturbances frequently precede bipolar disorder by several years and convey an elevated long-term risk for developing any kind of mood disorder. Disordered sleep appears to emerge about the time of puberty and remains persistently elevated in individuals at high risk. CONCLUSION: Disturbed sleep appears to be an early symptom of bipolar disorder but further research, especially longitudinal studies in individuals at high risk, will be required to characterize the type and patterns more precisely.
Authors: Heather L Rusch; Michael Rosario; Lisa M Levison; Anlys Olivera; Whitney S Livingston; Tianxia Wu; Jessica M Gill Journal: Ann N Y Acad Sci Date: 2018-12-21 Impact factor: 5.691
Authors: Jessica C Levenson; Adriane Soehner; Brian Rooks; Tina R Goldstein; Rasim Diler; John Merranko; David Axelson; Ben I Goldstein; David A Brent; Danella Hafeman; Mary Beth Hickey; Kelly Monk; Dara Sakolsky; David J Kupfer; Boris Birmaher Journal: J Affect Disord Date: 2017-03-06 Impact factor: 4.839
Authors: Adriane M Soehner; Michele A Bertocci; Anna Manelis; Genna Bebko; Cecile D Ladouceur; Simona Graur; Kelly Monk; Lisa K Bonar; Mary Beth Hickey; David Axelson; Benjamin I Goldstein; Tina R Goldstein; Boris Birmaher; Mary L Phillips Journal: J Affect Disord Date: 2016-07-01 Impact factor: 4.839