| Literature DB >> 21673456 |
Tetsuro Ago1, Junya Kuroda, Masahiro Kamouchi, Junichi Sadoshima, Takanari Kitazono.
Abstract
It has been established that oxidative stress plays a crucial role in the development and progression of vascular diseases. Besides the mitochondria, the NADPH oxidase/Nox family proteins are now thought to be important origins of the reactive oxygen species that underlie various vascular disease states, such as hypertension, atherosclerosis, angiogenesis, and ischemia/reperfusion injury. This review summarizes the basis of vascular Nox proteins and discusses their pathophysiological roles in the vascular system.Entities:
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Year: 2011 PMID: 21673456 DOI: 10.1253/circj.cj-11-0388
Source DB: PubMed Journal: Circ J ISSN: 1346-9843 Impact factor: 2.993