| Literature DB >> 21671632 |
Jennifer Peed1, Ignacio Periñán Domínguez, Iwan R Davies, Matt Cheeseman, James E Taylor, Gabriele Kociok-Köhn, Steven D Bull.
Abstract
A versatile methodology for the asymmetric synthesis of chiral δ-lactones containing multiple contiguous stereocenters has been developed that relies on a series of Evans' aldol, hydroxyl-directed cyclopropanation, methanolysis, and Hg(II) mediated cyclopropane ring-opening reactions for stereocontrol.Entities:
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Year: 2011 PMID： 21671632 DOI： 10.1021/ol2012023
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005