OBJECTIVE: We present our experience in parotid surgery for pleomorphic adenomas; analyzing a prospectively recorded database of parotidectomy; aiming to identify independent variables related to adenoma recurrence. STUDY DESIGN: Prospective case series. METHODS: Data of 182 patients; 164 new tumors and 18 revision parotidectomies were analyzed. The main outcome measure was tumor recurrence; the analyzed variables were age, gender, tumor size and site, safety margin, tumor puncture, spillage, adherence to facial nerve, surgical procedure, and follow-up period. RESULTS: Five new patients had a recurrence, two revision cases had second recurrence (11%), the overall recurrence rate was 3.8%. Recurrence rate was not related to age, gender, or duration of follow-up. Recurrence was related to larger tumors, tumors less than 30 mm in diameter are unlikely to recur. Tumor recurrence was inversely related to safety margin. Tumors with a diameter of 4 cm or more have no margins. All the seven tumors that recurred were punctured. Spillage was reported in five patients, four had a recurrence (80%). Tumor capsules were related to facial nerve in 75 cases; 6 of them had a recurrence (8%). CONCLUSIONS: Tumor puncture and spillage were the only variables that have an independent effect on recurrence, 26.9% of punctured tumors and 80% of cases of spillage recurred (P = .043 and P = .035, respectively). Although tumor size, safety margin, and adherence to facial nerve are related to recurrence, logistic regression suggests that these are confounding variables influencing recurrence through effect on puncture and spillage rates.
OBJECTIVE: We present our experience in parotid surgery for pleomorphic adenomas; analyzing a prospectively recorded database of parotidectomy; aiming to identify independent variables related to adenoma recurrence. STUDY DESIGN: Prospective case series. METHODS: Data of 182 patients; 164 new tumors and 18 revision parotidectomies were analyzed. The main outcome measure was tumor recurrence; the analyzed variables were age, gender, tumor size and site, safety margin, tumor puncture, spillage, adherence to facial nerve, surgical procedure, and follow-up period. RESULTS: Five new patients had a recurrence, two revision cases had second recurrence (11%), the overall recurrence rate was 3.8%. Recurrence rate was not related to age, gender, or duration of follow-up. Recurrence was related to larger tumors, tumors less than 30 mm in diameter are unlikely to recur. Tumor recurrence was inversely related to safety margin. Tumors with a diameter of 4 cm or more have no margins. All the seven tumors that recurred were punctured. Spillage was reported in five patients, four had a recurrence (80%). Tumor capsules were related to facial nerve in 75 cases; 6 of them had a recurrence (8%). CONCLUSIONS:Tumor puncture and spillage were the only variables that have an independent effect on recurrence, 26.9% of punctured tumors and 80% of cases of spillage recurred (P = .043 and P = .035, respectively). Although tumor size, safety margin, and adherence to facial nerve are related to recurrence, logistic regression suggests that these are confounding variables influencing recurrence through effect on puncture and spillage rates.
Authors: Miquel Quer; Vincent Vander Poorten; Robert P Takes; Carl E Silver; Carsten C Boedeker; Remco de Bree; Alessandra Rinaldo; Alvaro Sanabria; Ashok R Shaha; Albert Pujol; Peter Zbären; Alfio Ferlito Journal: Eur Arch Otorhinolaryngol Date: 2017-06-21 Impact factor: 2.503
Authors: Bayan Alzumaili; Bin Xu; Maelle Saliba; Abderhman Abuhashem; Ian Ganly; Ronald Ghossein; Nora Katabi Journal: Am J Surg Pathol Date: 2021-11-15 Impact factor: 6.298
Authors: Aline Semblano Carreira Falcão; Maria Sueli da Silva Kataoka; Nélson Antonio Bailão Ribeiro; José Antonio Picanço Diniz; Sérgio Melo Alves; André L Ribeiro Ribeiro; Adriane Sousa de Siqueira; Artur Luiz da Silva; Rommel Thiago Jucá Ramos; Vanessa M Freitas; Ruy G Jaeger; João J V Pinheiro Journal: PLoS One Date: 2014-08-19 Impact factor: 3.240