Literature DB >> 21670137

The prevalence of ear, nose and throat disorders in preschool children with Down's syndrome in Glasgow.

Emily Barr1, Jessica Dungworth, Karen Hunter, Margaret McFarlane, Haytham Kubba.   

Abstract

Guidelines suggest that all children with Down's syndrome have hearing testing on a regular basis. Since 2004, the ear, nose and throat (ENT), audiology and education services have conducted a joint clinic for annual ENT health and hearing surveillance of all preschool children with Down's syndrome in Greater Glasgow. The aim of this study is to report the prevalence of ENT problems in this well-defined birth cohort, and the proportion of children for whom ENT surgery is required. A prospective database has been kept since 2004, detailing the ENT health status of every child attending the community-based surveillance clinic. Between September 2004 and September 2008, 87 preschool (aged 9 months to 6 years) children with Down's syndrome were sent appointments for the clinic. Of these, 48 (55%) were female and 39 were male. Data were available for 79 (91%). Over the course of the study, 37% were listed for surgery at some point, either adenotonsillectomy for obstructive symptoms or grommet insertion for otitis media with effusion (OME). The prevalence of OME was 93% at age 1, falling to 68% by age 5. None had significant sensorineural hearing impairment. Obstructive symptoms were also common, with 79% of children having either currently symptomatic upper airways obstruction or a history of adenotonsillectomy by age 5. One child had laryngomalacia and two had symptomatic congenital subglottic stenosis. The prevalence of ENT problems in these children is high. Surgical intervention is frequently required. We advocate a proactive approach of regular ENT and audiology surveillance leading to early intervention, with the aim of maximizing health and educational achievement in the long term.

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Year:  2011        PMID: 21670137     DOI: 10.1258/smj.2011.011036

Source DB:  PubMed          Journal:  Scott Med J        ISSN: 0036-9330            Impact factor:   0.729


  7 in total

1.  A cross-sectional analysis of otitis media with effusion in children with Down syndrome.

Authors:  M Maris; M Wojciechowski; P Van de Heyning; An Boudewyns
Journal:  Eur J Pediatr       Date:  2014-05-10       Impact factor: 3.183

Review 2.  Parent-mediated interventions for promoting communication and language development in young children with Down syndrome.

Authors:  Ciara O'Toole; Alice S-Y Lee; Fiona E Gibbon; Anne K van Bysterveldt; Nicola J Hart
Journal:  Cochrane Database Syst Rev       Date:  2018-10-15

3.  Prevalence and incidence of physical health conditions in people with intellectual disability - a systematic review.

Authors:  Peiwen Liao; Claire Vajdic; Julian Trollor; Simone Reppermund
Journal:  PLoS One       Date:  2021-08-24       Impact factor: 3.240

4.  Update on first African clinical trial on earpopper for the treatment of otitis media with effusion [FCT/UATH/HREC/PR/330].

Authors:  Titus Sunday Ibekwe; Enoch Auta Dahilo; David Folorunso; Tochukwu Uzochukwu; Bosa I Egbe; Oladeji Raheem Quadri; Damtong Fred; Iboro Etukumana; Basil C Nwankwo; Ibeneche Onyemuchechi Gbujie
Journal:  Ann Afr Med       Date:  2022 Jan-Mar

Review 5.  Immune Dysregulation and the Increased Risk of Complications and Mortality Following Respiratory Tract Infections in Adults With Down Syndrome.

Authors:  Tomer Illouz; Arya Biragyn; Maria Florencia Iulita; Lisi Flores-Aguilar; Mara Dierssen; Ilario De Toma; Stylianos E Antonarakis; Eugene Yu; Yann Herault; Marie-Claude Potier; Alexandra Botté; Randall Roper; Benjamin Sredni; Jacqueline London; William Mobley; Andre Strydom; Eitan Okun
Journal:  Front Immunol       Date:  2021-06-25       Impact factor: 7.561

6.  Surveying the Down syndrome mouse model resource identifies critical regions responsible for chronic otitis media.

Authors:  Mahmood F Bhutta; Michael T Cheeseman; Yann Herault; Yuejin E Yu; Steve D M Brown
Journal:  Mamm Genome       Date:  2013-09-26       Impact factor: 2.957

Review 7.  Underlying factors of recurrent infections in patients with down syndrome.

Authors:  Turkan Patiroglu; Murat Cansever; Fulya Bektas
Journal:  North Clin Istanb       Date:  2018-01-29
  7 in total

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