Literature DB >> 21670

[Metabolism of DL-trans-2-dimethylamino-1-phenyl-cyclohex-3-ene-trans-1-carboxylic acid ester hydrochloride (Tilidine HC1). 3. Renal elimination of metabolites in the rat, dog and man].

K O Vollmer, A V Hodenberg.   

Abstract

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Year:  1977        PMID: 21670

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


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  4 in total

1.  Contribution of CYP2C19 and CYP3A4 to the formation of the active nortilidine from the prodrug tilidine.

Authors:  Barbara Grün; Ulrike Merkel; Klaus-Dieter Riedel; Johanna Weiss; Gerd Mikus
Journal:  Br J Clin Pharmacol       Date:  2012-11       Impact factor: 4.335

2.  In vitro identification of the cytochrome P450 isozymes involved in the N-demethylation of the active opioid metabolite nortilidine to bisnortilidine.

Authors:  Isabel Wustrow; Klaus-Dieter Riedel; Gerd Mikus; Johanna Weiss
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2012-02-15       Impact factor: 3.000

3.  [Management of chronic pain using extended release tilidine : Quality of life and implication of comedication on tilidine metabolism].

Authors:  C Wolfert; M Merbach; G Stammler; O Emrich; A D Meid; J Burhenne; A Blank; G Mikus
Journal:  Schmerz       Date:  2017-10       Impact factor: 1.107

4.  In vitro metabolism of the opioid tilidine and interaction of tilidine and nortilidine with CYP3A4, CYP2C19, and CYP2D6.

Authors:  Johanna Weiss; Evelyn Sawa; Klaus-Dieter Riedel; Walter Emil Haefeli; Gerd Mikus
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2008-05-31       Impact factor: 3.000

  4 in total

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