Literature DB >> 21668761

Project Lazarus: community-based overdose prevention in rural North Carolina.

Su Albert1, Fred W Brason, Catherine K Sanford, Nabarun Dasgupta, Jim Graham, Beth Lovette.   

Abstract

BACKGROUND: In response to some of the highest drug overdose death rates in the country, Project Lazarus developed a community-based overdose prevention program in Western North Carolina. The Wilkes County unintentional poisoning mortality rate was quadruple that of the state's in 2009 and due almost exclusively to prescription opioid pain relievers, including fentanyl, hydrocodone, methadone, and oxycodone. The program is ongoing.
METHODS: The overdose prevention program involves five components: community activation and coalition building; monitoring and surveillance data; prevention of overdoses; use of rescue medication for reversing overdoses by community members; and evaluating project components. Principal efforts include education of primary care providers in managing chronic pain and safe opioid prescribing, largely through the creation of a tool kit and face-to-face meetings.
RESULTS: Preliminary unadjusted data for Wilkes County revealed that the overdose death rate dropped from 46.6 per 100,000 in 2009 to 29.0 per 100,000 in 2010. There was a decrease in the number of victims who received prescriptions for the substance implicated in their fatal overdose from a Wilkes County physician; in 2008, 82% of overdose decedents received a prescription for an opioid analgesic from a Wilkes prescriber compared with 10% in 2010.
CONCLUSIONS: While the results from this community-based program are preliminary, the number and nature of prescription opioid overdose deaths in Wilkes County changed during the intervention. Further evaluation is required to understand the localized effect of the intervention and its potential for replication in other areas. Wiley Periodicals, Inc.

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Year:  2011        PMID: 21668761     DOI: 10.1111/j.1526-4637.2011.01128.x

Source DB:  PubMed          Journal:  Pain Med        ISSN: 1526-2375            Impact factor:   3.750


  75 in total

1.  High risk and little knowledge: overdose experiences and knowledge among young adult nonmedical prescription opioid users.

Authors:  David Frank; Pedro Mateu-Gelabert; Honoria Guarino; Alex Bennett; Travis Wendel; Lauren Jessell; Anastasia Teper
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Review 2.  Naloxone dosage for opioid reversal: current evidence and clinical implications.

Authors:  Rachael Rzasa Lynn; J L Galinkin
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3.  Critical opportunities for public health law: a call for action.

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4.  Emergency department utilization and subsequent prescription drug overdose death.

Authors:  Joanne E Brady; Charles J DiMaggio; Katherine M Keyes; John J Doyle; Lynne D Richardson; Guohua Li
Journal:  Ann Epidemiol       Date:  2015-04-02       Impact factor: 3.797

5.  How States Are Tackling the Opioid Crisis.

Authors:  Shalini Wickramatilake; Julia Zur; Norah Mulvaney-Day; Melinda Campopiano von Klimo; Elizabeth Selmi; Henrick Harwood
Journal:  Public Health Rep       Date:  2017-02-02       Impact factor: 2.792

6.  Community Readiness to Prevent Opioid Overdose.

Authors:  Christopher Ringwalt; Catherine Sanford; Nabarun Dasgupta; Apostolos Alexandridis; Agnieszka McCort; Scott Proescholdbell; Nidhi Sachdeva; Karin Mack
Journal:  Health Promot Pract       Date:  2018-02-05

7.  Opioid overdose prevention through pharmacy-based naloxone prescription program: Innovations in health care delivery.

Authors:  Amy Bachyrycz; Shikhar Shrestha; Barry E Bleske; Dale Tinker; Ludmila N Bakhireva
Journal:  Subst Abus       Date:  2016-05-10       Impact factor: 3.716

Review 8.  What we know, and don't know, about the impact of state policy and systems-level interventions on prescription drug overdose.

Authors:  Tamara M Haegerich; Leonard J Paulozzi; Brian J Manns; Christopher M Jones
Journal:  Drug Alcohol Depend       Date:  2014-10-14       Impact factor: 4.492

9.  Expanding access to naloxone in the United States.

Authors:  Suzanne Doyon; Steven E Aks; Scott Schaeffer
Journal:  J Med Toxicol       Date:  2014-12

10.  Effective Canadian policy to reduce harms from prescription opioids: learning from past failures.

Authors:  Benedikt Fischer; Jürgen Rehm; Mark Tyndall
Journal:  CMAJ       Date:  2016-11-07       Impact factor: 8.262

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