Literature DB >> 2166866

A social tethering system for nonhuman primates used in laboratory research.

A M Coelho1, K D Carey.   

Abstract

A housing and tether system was designed to permit sampling of body fluids, chronic monitoring of physiologic parameters (e.g. blood pressure, heart rate), performance of species typical behavioral interactions (aggression, affiliation, reproduction, etc), physical exercise (work on a motorized treadmill), assessment of water and diet consumption, as well as feces and urine collection. The system provided primates with the opportunity to engage in species typical social behavior and thereby minimized conditions which have been identified as contributing to the development of abnormal behaviors associated with individual housing. The system consisted of two parts: (a) a specialized cage system for housing small social groups of primates and (b) a tether and indwelling catheter system. Each modular system permitted four adult baboons (Papio cynocephalus anubis) to be tethered and housed in a social group. Each cage was 2.44 x 2.44 x 1.22 m (L x W x H) and could be subdivided by means of woven wire wall partitions. The tether system consisted of a backpack, a cloth jacket, a stainless-steel flexible cable containing electrical cables and catheters, and a saline infusion pump mounted on top of the cage. The system provides laboratory primates with the ability to socially interact with other nonhuman primates. The social cage tether system represents an example of a housing environment which could conform to both the letter and spirit of the new animal welfare legislation and still remain compatible with the objective of obtaining scientific data.

Entities:  

Mesh:

Year:  1990        PMID: 2166866

Source DB:  PubMed          Journal:  Lab Anim Sci        ISSN: 0023-6764


  10 in total

1.  Exenatide regulates pancreatic islet integrity and insulin sensitivity in the nonhuman primate baboon Papio hamadryas.

Authors:  Teresa Vanessa Fiorentino; Francesca Casiraghi; Alberto M Davalli; Giovanna Finzi; Stefano La Rosa; Paul B Higgins; Gregory A Abrahamian; Alessandro Marando; Fausto Sessa; Carla Perego; Rodolfo Guardado-Mendoza; Subhash Kamath; Andrea Ricotti; Paolo Fiorina; Giuseppe Daniele; Ana M Paez; Francesco Andreozzi; Raul A Bastarrachea; Anthony G Comuzzie; Amalia Gastaldelli; Alberto O Chavez; Eliana S Di Cairano; Patrice Frost; Livio Luzi; Edward J Dick; Glenn A Halff; Ralph A DeFronzo; Franco Folli
Journal:  JCI Insight       Date:  2019-10-17

2.  Protocol for the measurement of fatty acid and glycerol turnover in vivo in baboons.

Authors:  Raul A Bastarrachea; Sonya M Veron; Vidya Vaidyanathan; Maggie Garcia-Forey; V Saroja Voruganti; Paul B Higgins; Elizabeth J Parks
Journal:  J Lipid Res       Date:  2011-03-17       Impact factor: 5.922

3.  Successful pharmaceutical-grade streptozotocin (STZ)-induced hyperglycemia in a conscious tethered baboon (Papio hamadryas) model.

Authors:  Patrice A Frost; Shuyuan Chen; Marguerite J Mezzles; Venkata Saroja Voruganti; Edna J Nava-Gonzalez; Hector E Arriaga-Cazares; Katy A Freed; Anthony G Comuzzie; Ralph A DeFronzo; Jack W Kent; Paul A Grayburn; Raul A Bastarrachea
Journal:  J Med Primatol       Date:  2015-06-30       Impact factor: 0.667

4.  Central GIP signaling stimulates peripheral GIP release and promotes insulin and pancreatic polypeptide secretion in nonhuman primates.

Authors:  Paul B Higgins; Robert E Shade; Irám P Rodríguez-Sánchez; Magdalena Garcia-Forey; M Elizabeth Tejero; V Saroja Voruganti; Shelley A Cole; Anthony G Comuzzie; Franco Folli
Journal:  Am J Physiol Endocrinol Metab       Date:  2016-08-16       Impact factor: 4.310

5.  Chronic continuous exenatide infusion does not cause pancreatic inflammation and ductal hyperplasia in non-human primates.

Authors:  Teresa Vanessa Fiorentino; Michael Owston; Gregory Abrahamian; Stefano La Rosa; Alessandro Marando; Carla Perego; Eliana S Di Cairano; Giovanna Finzi; Carlo Capella; Fausto Sessa; Francesca Casiraghi; Ana Paez; Ashwin Adivi; Alberto Davalli; Paolo Fiorina; Rodolfo Guardado Mendoza; Anthony G Comuzzie; Mark Sharp; Ralph A DeFronzo; Glenn Halff; Edward J Dick; Franco Folli
Journal:  Am J Pathol       Date:  2014-11-06       Impact factor: 4.307

6.  Selective cannabinoid-1 receptor blockade benefits fatty acid and triglyceride metabolism significantly in weight-stable nonhuman primates.

Authors:  Vidya Vaidyanathan; Raul A Bastarrachea; Paul B Higgins; V Saroja Voruganti; Subhash Kamath; Nicholas V DiPatrizio; Daniele Piomelli; Anthony G Comuzzie; Elizabeth J Parks
Journal:  Am J Physiol Endocrinol Metab       Date:  2012-07-03       Impact factor: 4.310

7.  Successful β cells islet regeneration in streptozotocin-induced diabetic baboons using ultrasound-targeted microbubble gene therapy with cyclinD2/CDK4/GLP1.

Authors:  Shuyuan Chen; Raul A Bastarrachea; Brad J Roberts; V Saroja Voruganti; Patrice A Frost; Edna J Nava-Gonzalez; Hector E Arriaga-Cazares; Jiaxi Chen; Pintong Huang; Ralph A DeFronzo; Anthony G Comuzzie; Paul A Grayburn
Journal:  Cell Cycle       Date:  2014-02-10       Impact factor: 4.534

8.  Metabolic response to high-carbohydrate and low-carbohydrate meals in a nonhuman primate model.

Authors:  Elisa Fabbrini; Paul B Higgins; Faidon Magkos; Raul A Bastarrachea; V Saroja Voruganti; Anthony G Comuzzie; Robert E Shade; Amalia Gastaldelli; Jay D Horton; Daniela Omodei; Bruce W Patterson; Samuel Klein
Journal:  Am J Physiol Endocrinol Metab       Date:  2012-12-26       Impact factor: 4.310

9.  Enoxaparin treatment of spontaneous deep vein thrombosis in a chronically catheterized rhesus macaque (Macaca mulatta).

Authors:  Asheley B Wathen; Daniel D Myers; Paul Zajkowski; Graham Flory; F Claire Hankenson
Journal:  J Am Assoc Lab Anim Sci       Date:  2009-09       Impact factor: 1.232

10.  Energy expenditure evaluation in humans and non-human primates by SenseWear Armband. Validation of energy expenditure evaluation by SenseWear Armband by direct comparison with indirect calorimetry.

Authors:  Francesca Casiraghi; Raweewan Lertwattanarak; Livio Luzi; Alberto O Chavez; Alberto M Davalli; Terry Naegelin; Anthony G Comuzzie; Patricia Frost; Nicolas Musi; Franco Folli
Journal:  PLoS One       Date:  2013-09-19       Impact factor: 3.240

  10 in total

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