Michael Duchowny1. 1. Neurology Training and the Comprehensive Epilepsy Center, Miami Children's Hospital, Miami, FL, USA. Michael.Duchowny@mch.com
Abstract
INTRODUCTION: Performing epilepsy surgery in a child with a neurodegenerative illness is a relatively unexplored challenge. In this issue of CNS, Lupashko and coauthors report the use of epilepsy surgery to eliminate seizures without influencing the underlying progressive disorder. METHOD: Functional hemispherectomy was performed in a 4-year-old girl with seizures caused by Alpers' disease. RESULTS: Seizure freedom and an improved quality of life were achieved briefly despite deteriorating neurologic status. CONCLUSION: Further studies will be needed to confirm the positive benefits of palliative epilepsy surgery in children with progressive neurologic illnesses.
INTRODUCTION: Performing epilepsy surgery in a child with a neurodegenerative illness is a relatively unexplored challenge. In this issue of CNS, Lupashko and coauthors report the use of epilepsy surgery to eliminate seizures without influencing the underlying progressive disorder. METHOD: Functional hemispherectomy was performed in a 4-year-old girl with seizures caused by Alpers' disease. RESULTS:Seizure freedom and an improved quality of life were achieved briefly despite deteriorating neurologic status. CONCLUSION: Further studies will be needed to confirm the positive benefits of palliative epilepsy surgery in children with progressive neurologic illnesses.
Authors: M Sabaz; J A Lawson; D R Cairns; M S Duchowny; T J Resnick; P M Dean; A F Bleasel; A M E Bye Journal: Neurology Date: 2006-02-28 Impact factor: 9.910
Authors: Elysa Widjaja; Bing Li; Corrine Davies Schinkel; Lisa Puchalski Ritchie; James Weaver; O Carter Snead; James T Rutka; Peter C Coyte Journal: Epilepsy Res Date: 2011-03 Impact factor: 3.045
Authors: Mary L Zupanc; Elliane J dos Santos Rubio; Rhonda R Werner; Michael J Schwabe; Wade M Mueller; Sean M Lew; Charles J Marcuccilli; Sunila E O'Connor; Maria S Chico; Kathy A Eggener; Kurt E Hecox Journal: Pediatr Neurol Date: 2010-01 Impact factor: 3.372