OBJECTIVES: This study investigated the impact of smoking on the initial severity of acute ischemic stroke and examined its subsequent outcome. METHODS: Patient data was collected from the Stroke Registry in the Chang Gung Healthcare System (SRICHS). A total of 2650 patients admitted for acute ischemic stroke from January to December 2009 were included. Baseline characteristics were compared between smokers and non-smokers. Factors affecting the initial severity and the recovery from neurological deficit were examined by logistic regression analysis. The patients were further divided according to stroke mechanism for subgroup analysis. RESULTS: The total number of smokers and non-smokers was 817 (31.9%) and 1833 (69.1%), respectively. Univariate analysis showed that smokers had lower NIHSS scores on admission than did non-smokers (P<0.001). In subgroup analysis, smokers with small-vessel occlusions frequently had higher NIHSS scores on admission than did non-smokers (P=0.001). However, smokers with cardioembolic stroke had lower NIHSS scores on admission as compared to non-smokers (P=0.024). No subgroup had smoking as a significant factor for neurological recovery during hospitalization. CONCLUSIONS: Smoking correlated with higher NIHSS scores on admission for small-vessel occlusion. Conversely, it was associated with lower NIHSS scores on admission for cardioembolism.
OBJECTIVES: This study investigated the impact of smoking on the initial severity of acute ischemic stroke and examined its subsequent outcome. METHODS:Patient data was collected from the Stroke Registry in the Chang Gung Healthcare System (SRICHS). A total of 2650 patients admitted for acute ischemic stroke from January to December 2009 were included. Baseline characteristics were compared between smokers and non-smokers. Factors affecting the initial severity and the recovery from neurological deficit were examined by logistic regression analysis. The patients were further divided according to stroke mechanism for subgroup analysis. RESULTS: The total number of smokers and non-smokers was 817 (31.9%) and 1833 (69.1%), respectively. Univariate analysis showed that smokers had lower NIHSS scores on admission than did non-smokers (P<0.001). In subgroup analysis, smokers with small-vessel occlusions frequently had higher NIHSS scores on admission than did non-smokers (P=0.001). However, smokers with cardioembolic stroke had lower NIHSS scores on admission as compared to non-smokers (P=0.024). No subgroup had smoking as a significant factor for neurological recovery during hospitalization. CONCLUSIONS: Smoking correlated with higher NIHSS scores on admission for small-vessel occlusion. Conversely, it was associated with lower NIHSS scores on admission for cardioembolism.
Authors: Sheryl Hui-Xian Ng; Alex W K Wong; Cynthia Huijun Chen; Chuen Seng Tan; Falk Müller-Riemenschneider; Bernard P L Chan; M Carolyn Baum; Jin-Moo Lee; Narayanaswamy Venketasubramanian; Gerald Choon-Huat Koh Journal: Cerebrovasc Dis Date: 2019-08-21 Impact factor: 2.762
Authors: Ju-Hun Lee; Ju Young Lee; So Hyun Ahn; Min Uk Jang; Mi Sun Oh; Chul-Ho Kim; Kyung-Ho Yu; Byung-Chul Lee Journal: J Stroke Date: 2015-05-29 Impact factor: 6.967
Authors: Bae Youl Lee; Jinmann Chon; Hee-Sang Kim; Jong Ha Lee; Dong Hwan Yun; Seung Don Yoo; Dong Hwan Kim; Seung Ah Lee; Yoo Jin Han; Hyunseok Lee; Jin Chul Kim; Yunsoo Soh; Joo-Ho Chung; Su Kang Kim; Hae Jeong Park Journal: Ann Rehabil Med Date: 2017-04-27