Literature DB >> 21664206

Treatment of a large congenital melanocytic nevus with dermabrasion and autologous cell suspension (ReCELL®): a case report.

T B O'Neill1, J Rawlins, S Rea, F Wood.   

Abstract

Congenital melanocytic naevi (CMN) are present at birth in between 1 and 6% of all neonates. They are caused by malformations of the neuroectoderm that are comprised of melanocytes and occasionally neural elements, following dysregulated growth and arrest of melanocytes during migration from the neural crest to the skin. Most commonly they are sub-classified according to size. They are at risk of malignant transformation, but the psychological impact of prominent CMN's is arguably of greater potential concern to the parent and child. Treatment modalities to date have included complete surgical excision with defect reconstruction, as well as less invasive methods such as dermabrasion, curretage, chemical peels and laser therapy. We present an illustrated case of a healthy, term, 4 week-old male neonate with a large CMN on his face. The lesion was dermabraded, and non-cultured epithelial autograft harvested from the right post-auricular area was applied. Dressings were no longer required by the 8th post-operative day, and excellent skin pigmentation and texture was achieved by 5 months post-op.
Copyright © 2011 British Association of Plastic, Reconstructive and Aesthetic Surgeons. All rights reserved.

Entities:  

Mesh:

Year:  2011        PMID: 21664206     DOI: 10.1016/j.bjps.2011.05.016

Source DB:  PubMed          Journal:  J Plast Reconstr Aesthet Surg        ISSN: 1748-6815            Impact factor:   2.740


  4 in total

1.  Fat and epidermal cell suspension grafting: a new advanced one-step skin regeneration surgical technique.

Authors:  Emilia Migliano; Barbara Bellei; Flavio Andrea Govoni; Stefania Bucher; Mauro Picardo
Journal:  J Exp Clin Cancer Res       Date:  2014-02-24

2.  A Comparative Study of the ReCell® Device and Autologous Spit-Thickness Meshed Skin Graft in the Treatment of Acute Burn Injuries.

Authors:  James Hill Holmes Iv; Joseph A Molnar; Jeffrey E Carter; James Hwang; Bruce A Cairns; Booker T King; David J Smith; C Wayne Cruse; Kevin N Foster; Michael D Peck; Rajiv Sood; Michael J Feldman; Marion H Jordan; David W Mozingo; David G Greenhalgh; Tina L Palmieri; John A Griswold; Sharmila Dissanaike; William L Hickerson
Journal:  J Burn Care Res       Date:  2018-08-17       Impact factor: 1.845

3.  Giant congenital melanocytic nevus with developmental dysplasia of bilateral hip: a rare association.

Authors:  Sutsungkokla Imchen; Sangita Ghosh; Surabhi Dayal; Nisha Marwah; Nidhi Jindal; Shikha Sangal
Journal:  Indian J Dermatol       Date:  2013-11       Impact factor: 1.494

4.  Regenerative Surgery for the Definitive Repair of a Vasculitic Nonhealing Ulcer Using Platelet-derived Growth Factors and Noncultured Autologous Cell Suspension.

Authors:  Maria Trapasso; Francesco Spagnolo; Filippo Marchi; Paolo Strada; Pierluigi Santi; Marco Scala
Journal:  Plast Reconstr Surg Glob Open       Date:  2013-06-07
  4 in total

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