Literature DB >> 21662971

Synthesis of 8-arylquinolines via one-pot Pd-catalyzed borylation of quinoline-8-yl halides and subsequent Suzuki-Miyaura coupling.

Yongda Zhang1, Joe Gao, Wenjie Li, Heewon Lee, Bruce Z Lu, Chris H Senanayake.   

Abstract

A one-pot process has been developed for the synthesis of 8-arylquinolines via Pd-catalyzed borylation of quinoline-8-yl halides and subsequent Suzuki-Miyaura coupling with aryl halides using n-BuPAd(2) as ligand. Yields of up to 98% were obtained.

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Year:  2011        PMID： 21662971     DOI： 10.1021/jo200904g

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  6 in total

1.  Recent Advances in the C-H-Functionalization of the Distal Positions in Pyridines and Quinolines.

Authors:  David E Stephens; Oleg V Larionov
Journal:  Tetrahedron       Date:  2015-08-19       Impact factor: 2.457

2.  4,6,8-Triarylquinoline-3-carbaldehyde derivatives: synthesis and photophysical properties.

Authors:  Malose Jack Mphahlele; Adewale Olufunsho Adeloye
Journal:  Molecules       Date:  2013-12-17       Impact factor: 4.411

3.  Palladium-catalyzed borylation of aryl (pseudo)halides and its applications in biaryl synthesis.

Authors:  Hong Ji; Jianghong Cai; Nana Gan; Zhaohua Wang; Liyang Wu; Guorong Li; Tao Yi
Journal:  Chem Cent J       Date:  2018-12-19       Impact factor: 4.215

4.  A novel procedure for the synthesis of borylated quinolines and its application in the development of potential boron-based homeodomain interacting protein kinase 2 (HIPK2) inhibitors.

Authors:  Bhaskar C Das; Pratik Yadav; Sasmita Das; John Cijiang He
Journal:  RSC Adv       Date:  2022-08-25       Impact factor: 4.036

5.  A novel protocol for the one-pot borylation/Suzuki reaction provides easy access to hinge-binding groups for kinase inhibitors.

Authors:  A Hooper; A Zambon; C J Springer
Journal:  Org Biomol Chem       Date:  2015-12-01       Impact factor: 3.876

6.  Synthesis and photophysical properties of 2-aryl-6,8-bis(arylethenyl)-4-methoxyquinolines.

Authors:  Tebogo Ankie Khoza; Marole Maria Maluleka; Neliswa Mama; Malose Jack Mphahlele
Journal:  Molecules       Date:  2012-11-30       Impact factor: 4.411
  6 in total

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