Literature DB >> 2166262

The blocking effects of omega-conotoxin on Ca current in bovine chromaffin cells.

M Hans1, P Illes, K Takeda.   

Abstract

The effects of omega-conotoxin (omega-CgTX) on voltage-sensitive Ca currents (ICa) were studied in cultured bovine adrenal chromaffin cells. A maximal block of ICa of 40-50% was obtained with omega-CgTX in the microM range, and was independent of the holding potential. The onset of block was both concentration- and time-dependent. In bovine chromaffin cells, Ca channels, both sensitive and insensitive to omega-CgTX, appear to be present.

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Year:  1990        PMID： 2166262     DOI： 10.1016/0304-3940(90)90429-d

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  20 in total

1.  Coexpression of cloned alpha(1B), beta(2a), and alpha(2)/delta subunits produces non-inactivating calcium currents similar to those found in bovine chromaffin cells.

Authors:  A L Cahill; J H Hurley; A P Fox
Journal:  J Neurosci       Date:  2000-03-01       Impact factor: 6.167

2.  R-Type Ca2+ channels are coupled to the rapid component of secretion in mouse adrenal slice chromaffin cells.

Authors:  A Albillos; E Neher; T Moser
Journal:  J Neurosci       Date:  2000-11-15       Impact factor: 6.167

3.  Inhibition of voltage-dependent Ca2+ channels via alpha 2-adrenergic and opioid receptors in cultured bovine adrenal chromaffin cells.

Authors:  T Kleppisch; G Ahnert-Hilger; M Gollasch; K Spicher; J Hescheler; G Schultz; W Rosenthal
Journal:  Pflugers Arch       Date:  1992-06       Impact factor: 3.657

4.  Two types of calcium channels are expressed in adult bovine chromaffin cells.

Authors:  J L Bossu; M De Waard; A Feltz
Journal:  J Physiol       Date:  1991-06       Impact factor: 5.182

Review 5.  Noncholinergic control of adrenal catecholamine secretion.

Authors:  B G Livett; P D Marley
Journal:  J Anat       Date:  1993-10       Impact factor: 2.610

6.  Multiple calcium channel subtypes in isolated rat chromaffin cells.

Authors:  L Gandía; R Borges; A Albillos; A G García
Journal:  Pflugers Arch       Date:  1995-05       Impact factor: 3.657

7.  Calcium channel currents in bovine adrenal chromaffin cells and their modulation by anaesthetic agents.

Authors:  P Charlesworth; G Pocock; C D Richards
Journal:  J Physiol       Date:  1994-12-15       Impact factor: 5.182

8.  ATP modulation of calcium channels in chromaffin cells.

Authors:  L Gandía; A G García; M Morad
Journal:  J Physiol       Date:  1993-10       Impact factor: 5.182

9.  The effect of omega-conotoxin GVIA on synaptic transmission within the nucleus accumbens and hippocampus of the rat in vitro.

Authors:  A L Horne; J A Kemp
Journal:  Br J Pharmacol       Date:  1991-07       Impact factor: 8.739

10.  G-protein activation mediates prepulse facilitation of Ca2+ channel currents in bovine chromaffin cells.

Authors:  C A Doupnik; R Y Pun
Journal:  J Membr Biol       Date:  1994-05       Impact factor: 1.843
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