Literature DB >> 21660513

Novel botanical drug for the treatment of diabetic neuropathy.

Sang-Zin Choi1, Mi-Won Son.   

Abstract

Diabetic neuropathy has multiple aspects of pathophysiology including metabolic derangements and alterations of microvessel with hyperglycemia. Currently, there is no effective long-term treatment based on the pathologic mechanisms. Nerve regeneration with nerve growth factor (NGF) has been on clinical trials as a treatment option. This article reviews an action of a herbal medicine, DA 9801, whose mechanism of action is related to NGF in treating diabetic neuropathy.

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Year:  2011        PMID： 21660513     DOI： 10.1007/s12272-011-0621-2

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  9 in total

1.  Identification of Nitazoxanide as a Group I Metabotropic Glutamate Receptor Negative Modulator for the Treatment of Neuropathic Pain: An In Silico Drug Repositioning Study.

Authors:  Ni Ai; Richard D Wood; William J Welsh
Journal:  Pharm Res       Date:  2015-03-12       Impact factor: 4.200

Review 2.  Treatment of neuropathic pain with plant medicines.

Authors:  Garima Garg; James D Adams
Journal:  Chin J Integr Med       Date:  2012-08-02       Impact factor: 1.978

3.  Nerve growth factor and inducible nitric oxide synthase expression in the mesencephalon and diencephalon, as well as visual- and auditory-related nervous tissues, in a macaque model of type 2 diabetes.

Authors:  Qihui Luo; Wentao Liu; Jingyao Chen; Mingshu Wang; Wen Zeng; Zhengli Chen; Anchun Cheng
Journal:  Neural Regen Res       Date:  2012-02-05       Impact factor: 5.135

4.  Amelioration of Auditory Response by DA9801 in Diabetic Mouse.

Authors:  Yeong Ro Lee; Bin Na Hong; You Ri Her; Rodrigo Castañeda; Hyo Won Moon; Tong Ho Kang
Journal:  Evid Based Complement Alternat Med       Date:  2015-03-24       Impact factor: 2.629

5.  Dioscorea Extract (DA-9801) Modulates Markers of Peripheral Neuropathy in Type 2 Diabetic db/db Mice.

Authors:  Eunjung Moon; Sung Ok Lee; Tong Ho Kang; Hye Ju Kim; Sang Zin Choi; Mi-Won Son; Sun Yeou Kim
Journal:  Biomol Ther (Seoul)       Date:  2014-09-30       Impact factor: 4.634

Review 6.  Medicinal herbs in the treatment of neuropathic pain: a review.

Authors:  Fatemeh Forouzanfar; Hossein Hosseinzadeh
Journal:  Iran J Basic Med Sci       Date:  2018-04       Impact factor: 2.699

Review 7.  The Dioscorea Genus (Yam)-An Appraisal of Nutritional and Therapeutic Potentials.

Authors:  Jude E Obidiegwu; Jessica B Lyons; Cynthia A Chilaka
Journal:  Foods       Date:  2020-09-16

8.  Therapeutic Potential of Dioscorea Extract (DA-9801) in Comparison with Alpha Lipoic Acid on the Peripheral Nerves in Experimental Diabetes.

Authors:  Heung Yong Jin; Sun Hee Kim; Hea Min Yu; Hong Sun Baek; Tae Sun Park
Journal:  J Diabetes Res       Date:  2013-03-12       Impact factor: 4.011

9.  Evaluation of the transporter-mediated herb-drug interaction potential of DA-9801, a standardized dioscorea extract for diabetic neuropathy, in human in vitro and rat in vivo.

Authors:  Im-Sook Song; Tae Yeon Kong; Hyeon-Uk Jeong; Eun Nam Kim; Soon-Sang Kwon; Hee Eun Kang; Sang-Zin Choi; Miwon Son; Hye Suk Lee
Journal:  BMC Complement Altern Med       Date:  2014-07-17       Impact factor: 3.659
  9 in total

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