Literature DB >> 21660477

[Polypoid dysplasia in inflammatory bowel disease: differential diagnosis and further diagnostic and therapeutic approaches].

S Warich-Eitel1, T Katzenberger, M Eck.   

Abstract

Polypoid dysplasia in inflammatory bowel disease (IBD) is categorized as DALM (dysplasia associated lesion or mass) or ALM (adenoma-like mass). DALMs are etiologically related to the underlying inflammatory disease, have a high risk of cancer and remain an indication for colectomy. Sporadic adenomas occur coincidentally according to the adenoma-carcinoma sequence. They are adequately treated by polypectomy. More recently, a special group of lesions has been termed as "adenoma-like DALM" which shows a morphological overlap with sporadic adenomas in spite of arising against the background of chronic IBD. Adenoma-like DALMs may possess a lower risk of malignancy in contrast to non-adenoma-like DALMs. They may be treated adequately by polypectomy and continued monitoring if the lesion has been excised completely and there is no evidence of flat dysplasia elsewhere in the colon.

Entities:  

Mesh:

Year:  2011        PMID: 21660477     DOI: 10.1007/s00292-011-1433-3

Source DB:  PubMed          Journal:  Pathologe        ISSN: 0172-8113            Impact factor:   1.011


  25 in total

Review 1.  Ulcerative colitis-associated neoplasia.

Authors:  Shigehiko Fujii; Takahiro Fujimori; Hiroshi Kashida
Journal:  Pathol Int       Date:  2002-03       Impact factor: 2.534

Review 2.  [Diagnosis and therapy of ulcerative colitis: results of an evidence based consensus conference by the German society of Digestive and Metabolic Diseases and the competence network on inflammatory bowel disease].

Authors:  J C Hoffmann; M Zeitz; S C Bischoff; H J Brambs; H P Bruch; H J Buhr; A Dignass; I Fischer; W Fleig; U R Fölsch; K Herrlinger; W Höhne; G Jantschek; B Kaltz; K M Keller; U Knebel; A J Kroesen; W Kruis; H Matthes; G Moser; S Mundt; C Pox; M Reinshagen; A Reissmann; J Riemann; G Rogler; W Schmiegel; J Schölmerich; S Schreiber; O Schwandner; H K Selbmann; E F Stange; M Utzig; C Wittekind
Journal:  Z Gastroenterol       Date:  2004-09       Impact factor: 2.000

3.  What are the guidelines for treating adenoma-like DALMs in UC?

Authors:  Robert D Odze
Journal:  Inflamm Bowel Dis       Date:  2008-10       Impact factor: 5.325

4.  Mutations in the p53 gene: an early marker of neoplastic progression in ulcerative colitis.

Authors:  T A Brentnall; D A Crispin; P S Rabinovitch; R C Haggitt; C E Rubin; A C Stevens; G C Burmer
Journal:  Gastroenterology       Date:  1994-08       Impact factor: 22.682

5.  P53 and beta catenin expression in chronic ulcerative colitis--associated polypoid dysplasia and sporadic adenomas: an immunohistochemical study.

Authors:  S V Walsh; M Loda; C M Torres; D Antonioli; R D Odze
Journal:  Am J Surg Pathol       Date:  1999-08       Impact factor: 6.394

6.  Genetic alterations in chronic ulcerative colitis-associated adenoma-like DALMs are similar to non-colitic sporadic adenomas.

Authors:  R D Odze; C A Brown; C J Hartmann; A E Noffsinger; F Fogt
Journal:  Am J Surg Pathol       Date:  2000-09       Impact factor: 6.394

7.  Cytokeratin 7/20 and mucin core protein expression in ulcerative colitis-associated colorectal neoplasms.

Authors:  Natsuko Tatsumi; Ryoji Kushima; Michael Vieth; Ken-Ichi Mukaisho; Rie Kakinoki; Hidetoshi Okabe; Franz Borchard; Manfred Stolte; Takeshi Okanoue; Takanori Hattori
Journal:  Virchows Arch       Date:  2006-04-12       Impact factor: 4.064

Review 8.  [Endoscopic-bioptic diagnostics, surveillance of and therapy for gastrointestinal diseases according to guidelines].

Authors:  S Warich-Eitel; W Fischbach; M Eck
Journal:  Z Gastroenterol       Date:  2010-03-01       Impact factor: 2.000

9.  Dysplasia-associated lesion or mass (DALM) detected by colonoscopy in long-standing ulcerative colitis: an indication for colectomy.

Authors:  M O Blackstone; R H Riddell; B H Rogers; B Levin
Journal:  Gastroenterology       Date:  1981-02       Impact factor: 22.682

Review 10.  Management of neoplastic polyps in inflammatory bowel disease.

Authors:  Sonia Friedman; Robert D Odze; Francis A Farraye
Journal:  Inflamm Bowel Dis       Date:  2003-07       Impact factor: 5.325

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  1 in total

1.  [Precancerous colorectal tumors].

Authors:  I Tischoff; A Tannapfel
Journal:  Internist (Berl)       Date:  2013-06       Impact factor: 0.743

  1 in total

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