Literature DB >> 21659593

Cell signaling. New mTOR targets Grb attention.

Sung Su Yea1, David A Fruman.   

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Year:  2011        PMID： 21659593     DOI： 10.1126/science.1208071

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


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  15 in total

Review 1.  Roles of the PI3K/Akt pathway in Epstein-Barr virus-induced cancers and therapeutic implications.

Authors:  Jiezhong Chen
Journal:  World J Virol       Date:  2012-12-12

Review 2.  Lymphangioleiomyomatosis: A Monogenic Model of Malignancy.

Authors:  Vera P Krymskaya; Francis X McCormack
Journal:  Annu Rev Med       Date:  2017-01-14       Impact factor: 13.739

Review 3.  Regulation of mRNA translation by signaling pathways.

Authors:  Philippe P Roux; Ivan Topisirovic
Journal:  Cold Spring Harb Perspect Biol       Date:  2012-11-01       Impact factor: 10.005

4.  Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling.

Authors:  Bruno D Fonseca; Graham H Diering; Michael A Bidinosti; Kush Dalal; Tommy Alain; Aruna D Balgi; Roberto Forestieri; Matt Nodwell; Charles V Rajadurai; Cynthia Gunaratnam; Andrew R Tee; Franck Duong; Raymond J Andersen; John Orlowski; Masayuki Numata; Nahum Sonenberg; Michel Roberge
Journal:  J Biol Chem       Date:  2012-04-02       Impact factor: 5.157

5.  Perifosine enhances mTORC1-targeted cancer therapy by activation of GSK3β in NSCLC cells.

Authors:  Zhuo Ma; Lingjun Zhu; Xuan Luo; Sulan Zhai; Ping Li; Xuerong Wang
Journal:  Cancer Biol Ther       Date:  2012-07-24       Impact factor: 4.742

6.  VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.

Authors:  Stefan Hart; Veronica Novotny-Diermayr; Kee Chuan Goh; Meredith Williams; Yong Cheng Tan; Lai Chun Ong; Albert Cheong; Bee Kheng Ng; Chithra Amalini; Babita Madan; Harish Nagaraj; Ramesh Jayaraman; Khalid M Pasha; Kantharaj Ethirajulu; Wee Joo Chng; Nurulhuda Mustafa; Boon Cher Goh; Cyril Benes; Ultan McDermott; Mathew Garnett; Brian Dymock; Jeanette M Wood
Journal:  Mol Cancer Ther       Date:  2012-12-27       Impact factor: 6.261

7.  FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia.

Authors:  Julhash U Kazi; Lars Rönnstrand
Journal:  Mol Oncol       Date:  2012-11-29       Impact factor: 6.603

8.  Knockdown of PRAS40 inhibits insulin action via proteasome-mediated degradation of IRS1 in primary human skeletal muscle cells.

Authors:  C Wiza; D Herzfeld de Wiza; E B M Nascimento; S Lehr; H Al-Hasani; D M Ouwens
Journal:  Diabetologia       Date:  2013-03-05       Impact factor: 10.122

9.  Temporal regulation of rapamycin on memory CTL programming by IL-12.

Authors:  Xiangdong Li; Karla Garcia; Zhifeng Sun; Zhengguo Xiao
Journal:  PLoS One       Date:  2011-09-23       Impact factor: 3.240

10.  Akt and mTOR in B Cell Activation and Differentiation.

Authors:  Jose J Limon; David A Fruman
Journal:  Front Immunol       Date:  2012-08-06       Impact factor: 7.561
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