Literature DB >> 21659479

Carcinoid tumor metastases to the extraocular muscles: MR imaging and CT findings and review of the literature.

A Gupta1, J L Chazen, C D Phillips.   

Abstract

Although a relatively rare neoplasm, primary carcinoid tumor has an unusual propensity to metastasize to the orbits. Within the orbit, metastatic EOM lesions have been described in scattered reports in the ophthalmology literature but have received little to no attention in the radiology literature. After a retrospective review, we identified CT and MR imaging studies of 7 patients with carcinoid tumor metastatic to the EOM. Our findings suggest that in patients with known carcinoid tumor, well-defined, round, or fusiform masses of the EOM should strongly suggest metastatic involvement. Our series suggests that bilateral lesions may occur and that any EOM can be involved. Knowledge of this pattern of metastatic disease may spare biopsies in some patients, and with current orbit-sparing therapy for patients with localized orbital disease, early and accurate diagnosis can significantly improve patient outcomes.

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Year:  2011        PMID: 21659479      PMCID: PMC7966051          DOI: 10.3174/ajnr.A2470

Source DB:  PubMed          Journal:  AJNR Am J Neuroradiol        ISSN: 0195-6108            Impact factor:   3.825


  20 in total

1.  Multiple bilateral choroidal metastatic tumor from bronchial carcinoid: case report.

Authors:  P Perri; F Bandello; G Police; B Pastena; G Mingrone; S D'Angelo; A Sebastiani
Journal:  Retina       Date:  1998       Impact factor: 4.256

Review 2.  A clinicopathologic study of three carcinoid tumors metastatic to the orbit. Immunohistochemical, ultrastructural, and DNA flow cytometric studies.

Authors:  D J Shetlar; R L Font; N Ordóñez; A el-Naggar; M Boniuk
Journal:  Ophthalmology       Date:  1990-02       Impact factor: 12.079

3.  Carcinoid tumour metastatic to the orbit with infiltration to the extraocular orbital muscle.

Authors:  Olivera Casar Borota; Roar Kloster; Sigurd Lindal
Journal:  APMIS       Date:  2005-02       Impact factor: 3.205

Review 4.  Orbital carcinoid metastases.

Authors:  Jodhbir S Mehta; Yassir Abou-Rayyah; Geoffrey E Rose
Journal:  Ophthalmology       Date:  2006-02-03       Impact factor: 12.079

Review 5.  Metastatic carcinoid tumors: a clinical review.

Authors:  Johanna M Zuetenhorst; Babs G Taal
Journal:  Oncologist       Date:  2005-02

Review 6.  Carcinoid tumors.

Authors:  Scott N Pinchot; Kyle Holen; Rebecca S Sippel; Herbert Chen
Journal:  Oncologist       Date:  2008-12-17

7.  Metastatic atypical carcinoid tumor of the inferior rectus muscle.

Authors:  Hayyam Kiratli; Pinar Topcu Yilmaz; Zennure Isil Yildiz
Journal:  Ophthalmic Plast Reconstr Surg       Date:  2008 Nov-Dec       Impact factor: 1.746

8.  Clinical features and treatment of seven patients with carcinoid tumor metastatic to the eye and orbit.

Authors:  J T Fan; H Buettner; G B Bartley; J P Bolling
Journal:  Am J Ophthalmol       Date:  1995-02       Impact factor: 5.258

9.  A 5-decade analysis of 13,715 carcinoid tumors.

Authors:  Irvin M Modlin; Kevin D Lye; Mark Kidd
Journal:  Cancer       Date:  2003-02-15       Impact factor: 6.860

Review 10.  Uveal metastasis from carcinoid tumor. Clinical observations in nine cases.

Authors:  J W Harbour; P De Potter; C L Shields; J A Shields
Journal:  Ophthalmology       Date:  1994-06       Impact factor: 12.079

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  7 in total

1.  Orbital metastases from neuroendocrine neoplasms: clinical implications and outcomes.

Authors:  Lukasz Kamieniarz; Eleni Armeni; Luke Furtado O'Mahony; Charlotte Leigh; Lukon Miah; Akshay Narayan; Ankit Bhatt; Nicholas Cox; Dalvinder Mandair; Shaunak Navalkissoor; Martyn Caplin; Christos Toumpanakis
Journal:  Endocrine       Date:  2019-11-15       Impact factor: 3.633

Review 2.  Extraocular muscle enlargement.

Authors:  Khizar Rana; Valerie Juniat; Sandy Patel; Dinesh Selva
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2022-06-17       Impact factor: 3.535

3.  The role of radiological and hybrid imaging for muscle metastases: a systematic review.

Authors:  Amalia Lupi; Michael Weber; Paolo Del Fiore; Marco Rastrelli; Giuseppe Guglielmi; Roberto Stramare; Emilio Quaia; Diego Cecchin; Chiara Giraudo
Journal:  Eur Radiol       Date:  2019-12-13       Impact factor: 5.315

4.  The eye of the beholder: orbital metastases from midgut neuroendocrine tumors, a two institution experience.

Authors:  Satya Das; Gino Pineda; Laura Goff; Rachel Sobel; Jordan Berlin; George Fisher
Journal:  Cancer Imaging       Date:  2018-12-06       Impact factor: 3.909

5.  Normative measurements of the superior oblique and inferior oblique muscles by magnetic resonance imaging.

Authors:  Khizar Rana; Valerie Juniat; Aaron Rayan; Sandy Patel; Dinesh Selva
Journal:  Surg Radiol Anat       Date:  2022-03-08       Impact factor: 1.246

6.  Sinonasal Rhabdomyosarcoma Metastasis in Bilateral Multiple Extraocular Muscles: A Case Report and Brief Literature Review.

Authors:  So-Hyun Ji; Ji Hye Jang
Journal:  Taehan Yongsang Uihakhoe Chi       Date:  2020-12-23

7.  Report of metastatic ileal neuroendocrine tumor to the submandibular gland.

Authors:  David Forner; Peter Cho; Martin Bullock; Daniel Rayson; S Mark Taylor; Robert D Hart; Jonathan R Trites; Matthew H Rigby
Journal:  Int J Surg Case Rep       Date:  2018-10-19
  7 in total

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