Literature DB >> 2165881

Acyclovir in the treatment of herpesvirus infections.

B H Thiers1.   

Abstract

The development of the synthetic acyclic purine nucleoside analog acyclovir was a milestone in the field of antiviral chemotherapy. Acyclovir possesses unique biologic properties that make it especially useful for the treatment of herpesvirus infections. This article presents guidelines for the use of acyclovir in both immunocompetent and immunocompromised patients. The problem of acyclovir resistance is also discussed.

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Year:  1990        PMID： 2165881

Source DB:  PubMed          Journal:  Dermatol Clin        ISSN： 0733-8635            Impact factor:   3.478


  1 in total

1.  Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases.

Authors:  Priscila O de Giuseppe; Nadia H Martins; Andreia N Meza; Camila R dos Santos; Humberto D'Muniz Pereira; Mario T Murakami
Journal:  PLoS One       Date:  2012-09-05       Impact factor: 3.240
  1 in total

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