| Literature DB >> 21655610 |
Wentao Wang1, Xiangjin Lian, Donghui Chen, Xiaohua Liu, Lili Lin, Xiaoming Feng.
Abstract
An efficient yttrium(III)-catalyzed highly enantioselective Friedel-Crafts alkylation of β-trichloro(trifluoro)methyl aryl enones is described. The reaction delivered a series of functionalized indoles with a chiral tertiary carbon center bearing a trichloro(trifluoro)methyl group in excellent results (up to 96% ee and 99% yield) under mild conditions.Entities:
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Year: 2011 PMID： 21655610 DOI： 10.1039/c1cc12306h
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222