Literature DB >> 21654959

Insulinoma: a rare cause of a common metabolic disorder - hypoglycaemia.

Omayma El Shafie1, Dilip Sankhla, Nayil Al-Kindy, Aisha Al-Hamadani, Christopher Grant, Nicholas Woodhouse.   

Abstract

We describe the first patient diagnosed with an insulinoma in Oman and successfully managed with a distal laparoscopic pancreatectomy. The importance of obtaining a good history from the patient and/or his family is stressed. All patients with loss of consciousness must have a Reflow check carried out and, if hypoglycaemic, this should be documented in the laboratory and a simultaneous serum sample stored for measurement of insulin, C-peptide proinsulin and sulphonylurea levels, if subsequently indicated. If magnetic resonance imaging fails to locate the tumour, endoscopic ultrasound of the pancreas, or indium 111 labelled octreotide scanning is indicated if the patient's hypoglycaemia has previously responded to treatment with octreotide.

Entities:  

Keywords:  C-peptide; Hypoglycaemia; Insulinoma; Laparoscopy; Pancreatectomy

Year:  2008        PMID: 21654959      PMCID: PMC3087741     

Source DB:  PubMed          Journal:  Sultan Qaboos Univ Med J        ISSN: 2075-051X


  7 in total

1.  Forty-eight-hour fast: the diagnostic test for insulinoma.

Authors:  B Hirshberg; A Livi; D L Bartlett; S K Libutti; H R Alexander; J L Doppman; M C Skarulis; P Gorden
Journal:  J Clin Endocrinol Metab       Date:  2000-09       Impact factor: 5.958

2.  Hypoglycemic disorders.

Authors:  F J Service
Journal:  N Engl J Med       Date:  1995-04-27       Impact factor: 91.245

3.  Laparoscopic approach for solitary insulinoma: a multicentre study.

Authors:  A Ayav; L Bresler; L Brunaud; P Boissel
Journal:  Langenbecks Arch Surg       Date:  2004-12-18       Impact factor: 3.445

4.  Non-islet origin of pancreatic islet cell tumors.

Authors:  Alexander O Vortmeyer; Steve Huang; Irina Lubensky; Zhengping Zhuang
Journal:  J Clin Endocrinol Metab       Date:  2004-04       Impact factor: 5.958

5.  Insulinomas and expression of an insulin splice variant.

Authors:  Alexandra H Minn; Mark Kayton; Dominique Lorang; Steven C Hoffmann; David M Harlan; Steven K Libutti; Anath Shalev
Journal:  Lancet       Date:  2004-01-31       Impact factor: 79.321

6.  [Value of endoscopic ultrasonography and somatostatin receptor scintigraphy in the preoperative localization of insulinomas and gastrinomas. Experience of 54 cases].

Authors:  Eric Mirallié; François Pattou; Philippe Malvaux; Bernard Filoche; Jean-Michel Godchaux; Vincent Maunoury; Laurent Palazzo; Jean Lefebvre; Damien Huglo; Jean-Claude Paris; Bruno Carnaille; Charles Proye
Journal:  Gastroenterol Clin Biol       Date:  2002-04

7.  Complete clinical remission and disappearance of liver metastases after treatment with somatostatin analogue in a 40-year-old woman with a malignant insulinoma positive for somatostatin receptors type 2.

Authors:  Stefano Romeo; Massimo Milione; Alessandra Gatti; Mara Fallarino; Vito Corleto; Susanna Morano; Marco Giorgio Baroni
Journal:  Horm Res       Date:  2006-02-09
  7 in total

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