Literature DB >> 21653957

Product development partnerships hit their stride: lessons from developing a meningitis vaccine for Africa.

David M Bishai1, Claire Champion, Michael E Steele, Lindsay Thompson.   

Abstract

The Meningitis Vaccine Project, a so-called product development partnership, developed a new vaccine against bacterial meningitis, an inflammation of brain tissues that causes an estimated 10,000 deaths among African children and young people each year. The vaccine--known as MenAfriVac and specifically targeted for use in low-income countries in Africa--was designed to be made available to governments at a price of fifty cents per dose. The Meningitis Vaccine Project is an example of how product development partnerships have reinvigorated research on vaccines for neglected diseases. These partnerships disperse the multiple tasks of product development across a network of partners that are best suited for each task. The vaccine was rapidly embraced by African health officials, and in its first few weeks on the market, in late 2010, more than nineteen million people in Burkina Faso, Mali, and Niger were vaccinated.

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Year:  2011        PMID: 21653957     DOI: 10.1377/hlthaff.2011.0295

Source DB:  PubMed          Journal:  Health Aff (Millwood)        ISSN: 0278-2715            Impact factor:   6.301


  15 in total

1.  Enhancing the work of the Department of Health and Human Services national vaccine program in global immunization: recommendations of the National Vaccine Advisory Committee: approved by the National Vaccine Advisory Committee on September 12, 2013.

Authors: 
Journal:  Public Health Rep       Date:  2014       Impact factor: 2.792

2.  HHS--supporting global immunization through policies, programs, and partnerships.

Authors:  Nils Daulaire
Journal:  Public Health Rep       Date:  2014       Impact factor: 2.792

Review 3.  Sustainable Financing of Innovative Therapies: A Review of Approaches.

Authors:  Aidan Hollis
Journal:  Pharmacoeconomics       Date:  2016-10       Impact factor: 4.981

Review 4.  Challenges for nationwide vaccine delivery in African countries.

Authors:  Mario Songane
Journal:  Int J Health Econ Manag       Date:  2017-10-19

Review 5.  Neurology and international organizations.

Authors:  Farrah J Mateen
Journal:  Neurology       Date:  2013-07-23       Impact factor: 9.910

6.  Mutant Native Outer Membrane Vesicles Combined with a Serogroup A Polysaccharide Conjugate Vaccine for Prevention of Meningococcal Epidemics in Africa.

Authors:  Rolando Pajon; Andrew M Fergus; Dan M Granoff
Journal:  PLoS One       Date:  2013-06-21       Impact factor: 3.240

7.  Successful African introduction of a new Group A meningococcal conjugate vaccine: Future challenges and next steps.

Authors:  F Marc LaForce; Mamoudou Djingarey; Simonetta Viviani; Marie-Pierre Preziosi
Journal:  Hum Vaccin Immunother       Date:  2017-11-08       Impact factor: 3.452

8.  Strengthening medical product regulation in low- and middle-income countries.

Authors:  Charles Preston; Mary Lou Valdez; Katherine Bond
Journal:  PLoS Med       Date:  2012-10-23       Impact factor: 11.069

9.  Meningococcal disease: changes in epidemiology and prevention.

Authors:  Qiuzhi Chang; Yih-Ling Tzeng; David S Stephens
Journal:  Clin Epidemiol       Date:  2012-09-19       Impact factor: 4.790

Review 10.  Technical Development of a New Meningococcal Conjugate Vaccine.

Authors:  Carl E Frasch; Subhash V Kapre; Che-Hung Lee; Jean-Marie Préaud
Journal:  Clin Infect Dis       Date:  2015-11-15       Impact factor: 9.079

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