Literature DB >> 21653214

Retinopathy of prematurity as a major cause of severe visual impairment and blindness in children in schools for the blind in Guadalajara city, Mexico.

L C Zepeda-Romero1, J C Barrera-de-Leon, C Camacho-Choza, C Gonzalez Bernal, E Camarena-Garcia, C Diaz-Alatorre, J A Gutierrez-Padilla, C Gilbert.   

Abstract

AIM: To determine the causes of blindness in students attending schools for the blind in Guadalajara city, Mexico and to assess the availability of screening for retinopathy of prematurity (ROP) in local neonatal intensive care units.
METHODS: Information on causes of blindness was obtained by interview with parents and teachers, review of records and examination. Causes of visual loss in children with a distance visual acuity of <6/60 (ie, severely visually impaired or blind) were determined and classified according to the WHO's classification system for children.
RESULTS: Of 153 children in the two participating schools, 144 were severely visual impaired or blind. Their ages ranged from 4 months to 15 years and 58% were female. ROP was the most common cause of visual loss (34.7%), followed by optic nerve lesions (17.4%) and glaucoma (14.6%). 25/59 (42.3%) children aged 0-4 years were blind from ROP compared with 6/32 (18.8%) children aged 10-15 years. 78% of children blind from ROP had psychomotor delay and less than half (46%) had not received treatment for ROP. All five privately funded neonatal intensive care units in the city regularly screen for ROP compared with only four of the 12 units in the public sector.
CONCLUSIONS: ROP is the leading cause of blindness in children in Mexico despite national guidelines being in place. Health policies promoting primary prevention through improved neonatal care need to be implemented. Advocacy is required so that the time ophthalmologists spend screening and treating ROP is included in their job description and hence salaried.

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Year:  2011        PMID: 21653214     DOI: 10.1136/bjophthalmol-2011-300015

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  13 in total

1.  Influence of polymorphisms in VEGF, ACE, TNF and GST genes on the susceptibility to retinopathy of prematurity among Chinese infants.

Authors:  Xiao-Jun Lei; Yong-Xia Zhao; Tong Qiao
Journal:  Int J Ophthalmol       Date:  2018-09-18       Impact factor: 1.779

2.  Oxygen-induced retinopathy induces short-term glial stress and long-term impairment of photoentrainment in mice.

Authors:  Madah Khawn-I-Muhammad Mehdi; Dominique Sage-Ciocca; Etienne Challet; André Malan; David Hicks
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-02-09       Impact factor: 3.117

3.  Propranolol 0.1% eye micro-drops in newborns with retinopathy of prematurity: a pilot clinical trial.

Authors:  Luca Filippi; Giacomo Cavallaro; Paola Bagnoli; Massimo Dal Monte; Patrizio Fiorini; Elettra Berti; Letizia Padrini; Gianpaolo Donzelli; Gabriella Araimo; Gloria Cristofori; Monica Fumagalli; Giancarlo la Marca; Maria Luisa Della Bona; Roberta Pasqualetti; Pina Fortunato; Silvia Osnaghi; Barbara Tomasini; Maurizio Vanni; Anna Maria Calvani; Silvano Milani; Ivan Cortinovis; Alessandra Pugi; Massimo Agosti; Fabio Mosca
Journal:  Pediatr Res       Date:  2016-11-04       Impact factor: 3.756

4.  Case series of infants presenting with end stage retinopathy of prematurity to two tertiary eye care facilities in Mexico: underlying reasons for late presentation.

Authors:  Luz C Zepeda-Romero; Alonso Meza-Anguiano; Juan C Barrera-de León; Eusebio Angulo-Castellanos; Marco A Ramirez-Ortiz; José A Gutiérrez-Padilla; Clare E Gilbert
Journal:  Matern Child Health J       Date:  2015-06

Review 5.  The progress of prophylactic treatment in retinopathy of prematurity.

Authors:  Hong-Bing Zhang; Xiao-Dong Wang; Kun Xu; Xiao-Gang Li
Journal:  Int J Ophthalmol       Date:  2018-05-18       Impact factor: 1.779

6.  Limitations in ROP Programs in 32 Neonatal Intensive Care Units in Five States in Mexico.

Authors:  L Consuelo Zepeda-Romero; Clare Gilbert
Journal:  Biomed Res Int       Date:  2015-06-17       Impact factor: 3.411

7.  Eye conditions and blindness in children: priorities for research, programs, and policy with a focus on childhood cataract.

Authors:  Clare Gilbert; Mohammed Muhit
Journal:  Indian J Ophthalmol       Date:  2012 Sep-Oct       Impact factor: 1.848

Review 8.  Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010.

Authors:  Hannah Blencowe; Joy E Lawn; Thomas Vazquez; Alistair Fielder; Clare Gilbert
Journal:  Pediatr Res       Date:  2013-12       Impact factor: 3.756

Review 9.  Born too soon: the global epidemiology of 15 million preterm births.

Authors:  Hannah Blencowe; Simon Cousens; Doris Chou; Mikkel Oestergaard; Lale Say; Ann-Beth Moller; Mary Kinney; Joy Lawn
Journal:  Reprod Health       Date:  2013-11-15       Impact factor: 3.223

10.  Influence of subretinal fluid in advanced stage retinopathy of prematurity on proangiogenic response and cell proliferation.

Authors:  Jie Ma; Manisha Mehta; Godfrey Lam; Desireé Cyr; Tat Fong Ng; Tatsuo Hirose; Khaled A Tawansy; Andrew W Taylor; Kameran Lashkari
Journal:  Mol Vis       Date:  2014-06-21       Impact factor: 2.367

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