Literature DB >> 21651838

Delay in operative stabilization of spine fractures in multitrauma patients without neurologic injuries: effects on outcomes.

Hossein Pakzad1, Darren M Roffey, Heather Knight, Simon Dagenais, Jean-Denis Yelle, Eugene K Wai.   

Abstract

BACKGROUND: Optimal timing for surgical stabilization of the fractured spine is controversial. Early stabilization facilitates mobilization and theoretically reduces associated complications.
METHODS: We identified consecutive patients without neurologic injury requiring stabilization surgery for a spinal fracture at an academic tertiary-care hospital over a 12-year period. Incidences of postoperative complications were prospectively evaluated. We analyzed results based on the time elapsed before the final surgical stabilization procedure. Multivariate analyses were performed to explore the effects of potential confounders.
RESULTS: A total of 83 patients (60 men, 23 women; mean age 39.4 yr) met the eligibility criteria and were enrolled. The mean Injury Severity Score (ISS) was 27.1 (range 12.0-57.0); 35% of patients had a cervical fracture and 65% had a thoraco-lumbar fracture. No statistically significant associations were uncovered between time to surgical stabilization and age, ISS or comorbidities. Comparing patients stabilized after 24 hours with those stabilized within 24 hours, there was an almost 8-fold greater risk of a complication related to prolonged recumbency (p = 0.007). We observed similar effects for other types of complications. Delays of more than 72 hours had a negative effect on complication rates; these effects remained significant after multivariate adjustments for age, comorbidity and ISS.
CONCLUSION: This study demonstrates a strong relation between timing of surgical stabilization of spinal fractures in multitrauma patients without neurologic injuries and complications. Further studies with larger samples may allow for better adjustment of potentially confounding factors and identify subgroups in which this effect is most pronounced.

Entities:  

Mesh:

Year:  2011        PMID: 21651838      PMCID: PMC3191902          DOI: 10.1503/cjs.008810

Source DB:  PubMed          Journal:  Can J Surg        ISSN: 0008-428X            Impact factor:   2.089


  28 in total

1.  Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases.

Authors:  R A Deyo; D C Cherkin; M A Ciol
Journal:  J Clin Epidemiol       Date:  1992-06       Impact factor: 6.437

2.  An overview of the issues: physiological effects of bed rest and restricted physical activity.

Authors:  V A Convertino; S A Bloomfield; J E Greenleaf
Journal:  Med Sci Sports Exerc       Date:  1997-02       Impact factor: 5.411

3.  Early versus delayed stabilization of femoral fractures. A prospective randomized study.

Authors:  L B Bone; K D Johnson; J Weigelt; R Scheinberg
Journal:  J Bone Joint Surg Am       Date:  1989-03       Impact factor: 5.284

4.  The impact of confounder selection criteria on effect estimation.

Authors:  R M Mickey; S Greenland
Journal:  Am J Epidemiol       Date:  1989-01       Impact factor: 4.897

5.  Timing of surgical decompression and fixation of acute spinal fractures.

Authors:  J Schlegel; J Bayley; H Yuan; B Fredricksen
Journal:  J Orthop Trauma       Date:  1996       Impact factor: 2.512

6.  Neurologic recovery associated with anterior decompression of spine fractures at the thoracolumbar junction (T12-L1).

Authors:  J C Clohisy; B A Akbarnia; R D Bucholz; J K Burkus; R J Backer
Journal:  Spine (Phila Pa 1976)       Date:  1992-08       Impact factor: 3.468

7.  Long bone fractures in the polytrauma patient. The role of early operative fixation.

Authors:  S B Beckman; D J Scholten; B W Bonnell; C D Bukrey
Journal:  Am Surg       Date:  1989-06       Impact factor: 0.688

8.  Early stabilization and decompression for incomplete paraplegia due to a thoracic-level spinal cord injury.

Authors:  W F Krengel; P A Anderson; M B Henley
Journal:  Spine (Phila Pa 1976)       Date:  1993-10-15       Impact factor: 3.468

9.  Comparison of surgical and conservative management in 208 patients with acute spinal cord injury.

Authors:  C H Tator; E G Duncan; V E Edmonds; L I Lapczak; D F Andrews
Journal:  Can J Neurol Sci       Date:  1987-02       Impact factor: 2.104

10.  Incidence of adult respiratory distress syndrome in patients with multiple musculoskeletal injuries: effect of early operative stabilization of fractures.

Authors:  K D Johnson; A Cadambi; G B Seibert
Journal:  J Trauma       Date:  1985-05
View more
  10 in total

1.  Prolonged bed rest as adjuvant therapy after complex reconstructive spine surgery.

Authors:  Rex A W Marco; Ryan M Stuckey; Stephanie P Holloway
Journal:  Clin Orthop Relat Res       Date:  2012-06       Impact factor: 4.176

2.  Timing of intervention for spinal injury in patients with polytrauma.

Authors:  Rishi Mugesh Kanna; Ajoy Prasad Shetty; S Rajasekaran
Journal:  J Clin Orthop Trauma       Date:  2020-10-09

3.  Brothers-in-arms: Liaison between spine surgeons and plastic surgeons in wound repair after complex spine surgery.

Authors:  Bhavuk Garg; Nishank Mehta
Journal:  N Am Spine Soc J       Date:  2020-10-02

4.  Traumatic spinal cord injury in southern Saudi Arabia: Patterns, time to surgery and outcomes.

Authors:  Ibrahim Alnaami; Saleh Alsaleh; Mohammed S Al-Amri; Ayman Al-Alamri; Fares Al-Zahrani; Mohammed A Al-Amri; Mohammed Abid Khan
Journal:  J Family Med Prim Care       Date:  2021-04-29

5.  Treatment results in the differential surgery of intradural extramedullary schwannoma of 110 cases.

Authors:  Shaohui Zong; Gaofeng Zeng; Chunxiang Xiong; Bo Wei
Journal:  PLoS One       Date:  2013-05-27       Impact factor: 3.240

6.  Orthopaedic surgical treatment delays at a tertiary hospital in sub Saharan Africa: Communication gaps and implications for clinical outcomes.

Authors:  Adeleke O Ifesanya; Olumuyiwa J Ogundele; Joy U Ifesanya
Journal:  Niger Med J       Date:  2013-11

7.  Improving access to emergent spinal care through knowledge translation: an ethnographic study.

Authors:  Fiona Webster; Michael G Fehlings; Kathleen Rice; Harsha Malempati; Khaled Fawaz; Fred Nicholls; Navindra Baldeo; Scott Reeves; Anoushka Singh; Henry Ahn; Howard Ginsberg; Albert J Yee
Journal:  BMC Health Serv Res       Date:  2014-04-14       Impact factor: 2.655

8.  Complications and long-term outcomes after open surgery for traumatic subaxial cervical spine fractures: a consecutive series of 303 patients.

Authors:  Hege Linnerud Fredø; Syed Ali Mujtaba Rizvi; Mehran Rezai; Pål Rønning; Bjarne Lied; Eirik Helseth
Journal:  BMC Surg       Date:  2016-08-15       Impact factor: 2.102

9.  Is Early Appropriate Care of axial and femoral fractures appropriate in multiply-injured elderly trauma patients?

Authors:  M S Reich; A J Dolenc; T A Moore; H A Vallier
Journal:  J Orthop Surg Res       Date:  2016-09-26       Impact factor: 2.359

10.  Characteristics, incidence, and risk factors for death from fatal pneumonia among patients with primary malignant bone tumors: a SEER-based observational study.

Authors:  Kaixu Yu; Ying Chen; Yahao Tian; Honglei Kang; Kehan Song; Yimin Dong; Renpeng Peng; Feng Li
Journal:  Transl Cancer Res       Date:  2021-08       Impact factor: 1.241

  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.