AIM: To evaluate the diagnostic accuracy of biopsy by dilatation and curettage in postmenopausal women with abnormal uterine bleeding. MATERIAL AND METHODS: A prospective observational study conducted with 112 consecutive postmenopausal women. Biopsy by dilatation and curettage was immediately followed by hysteroscopic biopsy and the histologic results were compared. RESULTS: By curettage, although performed under anesthesia, 3/3 (100%) cases of endometrial hyperplasia were reported as normal proliferative endometrium. There were two endometrial cancers (1.8%) and one case was missed as normal endometrium by curettage. Among endometrial polyps, only 3/39 (7.7%) cases were diagnosed by curettage. CONCLUSIONS: In postmenopausal women with abnormal uterine bleeding, biopsy by curettage may be not reliable for evaluation of endometrial pathology.
AIM: To evaluate the diagnostic accuracy of biopsy by dilatation and curettage in postmenopausal women with abnormal uterine bleeding. MATERIAL AND METHODS: A prospective observational study conducted with 112 consecutive postmenopausal women. Biopsy by dilatation and curettage was immediately followed by hysteroscopic biopsy and the histologic results were compared. RESULTS: By curettage, although performed under anesthesia, 3/3 (100%) cases of endometrial hyperplasia were reported as normal proliferative endometrium. There were two endometrial cancers (1.8%) and one case was missed as normal endometrium by curettage. Among endometrial polyps, only 3/39 (7.7%) cases were diagnosed by curettage. CONCLUSIONS: In postmenopausal women with abnormal uterine bleeding, biopsy by curettage may be not reliable for evaluation of endometrial pathology.
Authors: Pasquale De Franciscis; Gaetano Riemma; Antonio Schiattarella; Luigi Cobellis; Maria Guadagno; Salvatore Giovanni Vitale; Lavinia Mosca; Antonio Cianci; Nicola Colacurci Journal: Diagnostics (Basel) Date: 2019-10-07