Literature DB >> 21647832

[Chondrosarcoma of the larynx. Experience gained in Freiburg since 1999].

C C Boedeker1, W Maier, M Boedeker, G J Ridder, T Klenzner, G Kayser, C Offergeld.   

Abstract

BACKGROUND: Chondrosarcomas are rare tumors of the head and neck. Nevertheless, they display the most common non-epithelial malignancy of the larynx.
MATERIALS AND METHODS: Between 1999 and February 2010 we treated six patients with laryngeal chondrosarcoma. The group included two female and four male patients ranging in age from 54 to 82 years.
RESULTS: An 82-year-old female patient died 3 months after diagnosis and tracheostomy due to other underlying diseases. An 82-year-old male patient underwent primary radiation therapy. In the other patients, we performed a modified hemilaryngektomy in three cases and a laryngectomy in one. In those four cases, there were no signs of recurrent disease 50, 85, 87 and 95 months after surgery, respectively. There were no local or distant metastases.
CONCLUSIONS: Chondrosarcomas of the larynx are slow growing neoplasms. Metastases occur in less than 3% of cases. Complete resection is the therapy of choice. Function-preserving surgical approaches should be favoured.

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Year:  2011        PMID: 21647832     DOI: 10.1007/s00106-010-2243-2

Source DB:  PubMed          Journal:  HNO        ISSN: 0017-6192            Impact factor:   1.284


  28 in total

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Authors:  A Rinaldo; D J Howard; A Ferlito
Journal:  Acta Otolaryngol       Date:  2000-09       Impact factor: 1.494

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Journal:  Cancer       Date:  1977-08       Impact factor: 6.860

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Authors:  G Marchal; A L Baert; L van der Hauwaert
Journal:  Br J Radiol       Date:  1974-12       Impact factor: 3.039

4.  Cartilaginous tumors of the larynx: a series of 33 patients.

Authors:  H B Neel; K K Unni
Journal:  Otolaryngol Head Neck Surg       Date:  1982 Mar-Apr       Impact factor: 3.497

5.  Chondrosarcoma of the head and neck.

Authors:  B B Burkey; H T Hoffman; S R Baker; A F Thornton; K D McClatchey
Journal:  Laryngoscope       Date:  1990-12       Impact factor: 3.325

6.  [Chondrosarcoma of the larynx].

Authors:  B M Lippert; H Claassen; J Bäumken; U Jänig; J A Werner
Journal:  Laryngorhinootologie       Date:  1997-01       Impact factor: 1.057

7.  Sarcomas of the larynx.

Authors:  A Gorenstein; H B Neel; L H Weiland; K D Devine
Journal:  Arch Otolaryngol       Date:  1980-01

8.  Laryngeal chondrosarcomas: a clinicopathologic study of 11 cases, including two "dedifferentiated" chondrosarcomas.

Authors:  M Brandwein; S Moore; P Som; H Biller
Journal:  Laryngoscope       Date:  1992-08       Impact factor: 3.325

9.  Chondrosarcoma of the epiglottis.

Authors:  M Kasanzew; D G John; P Newman; T J Lesser; P L Thomas
Journal:  J Laryngol Otol       Date:  1988-04       Impact factor: 1.469

10.  Hemicricoidectomy as the primary diagnosis and treatment for cricoid chondrosarcomas.

Authors:  Jacob T Cohen; Gregory N Postma; Sumeer Gupta; James A Koufman
Journal:  Laryngoscope       Date:  2003-10       Impact factor: 3.325

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