Literature DB >> 2164701

[Cytomegalovirus encephalo-myelo-radiculitis in acquired immunodeficiency syndrome].

L Chimelli1, M R de Freitas, A R Bazin, C Mhiri, F Scaravilli, F Gray.   

Abstract

A 30 year-old male, with the acquired immune deficiency syndrome (AIDS) presented with rapidly progressive flaccid paraplegia and sphincter incontinence. Cerebrospinal fluid examination showed elevated protein and pleocytosis. Death occurred 2 months after the onset of neurological signs. Post-mortem examination showed inflammatory necrotic lesions, relatively sparing the axons and predominantly involving the roots of the cord. Numerous cytomegalovirus (CMV) inclusion bodies were found in the necrotic lesions, in the subarachnoid spaces and in Schwann cells. CMV encephalitis and involvement of the 3rd cranial nerves were also observed. Only 8 well-documented clinico-pathological cases of acute CMV myeloradiculitis, which all presented as progressive cauda equina syndrome, have been reported until now in AIDS patients.

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Mesh:

Year:  1990        PMID: 2164701

Source DB:  PubMed          Journal:  Rev Neurol (Paris)        ISSN: 0035-3787            Impact factor:   2.607


  3 in total

1.  Acute varicella-zoster virus ventriculitis and meningo-myelo-radiculitis in acquired immunodeficiency syndrome.

Authors:  F Chrétien; F Gray; M C Lescs; C Geny; M L Dubreuil-Lemaire; F Ricolfi; M Baudrimont; Y Levy; A Sobel; H V Vinters
Journal:  Acta Neuropathol       Date:  1993       Impact factor: 17.088

2.  Lymphoma-induced polyradiculopathy in AIDS: two cases.

Authors:  J M Léger; D Hénin; L Bélec; B Mercier; L Cohen; P Bouche; J J Hauw; P Brunet
Journal:  J Neurol       Date:  1992-03       Impact factor: 4.849

3.  Cytomegalovirus (CMV) encephalomyeloradiculitis and human immunodeficiency virus (HIV) encephalitis: presence of HIV and CMV co-infected multinucleated giant cells.

Authors:  L Bélec; F Gray; J Mikol; F Scaravilli; C Mhiri; A Sobel; J Poirier
Journal:  Acta Neuropathol       Date:  1990       Impact factor: 17.088

  3 in total

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