Literature DB >> 2164663

Severe haemolytic anaemia due to cold anti-'i' antibodies associated with cytomegalovirus infection.

J M Aguado1, J M Castrillo, J Sanz, J Serrano.   

Abstract

A 66 year old patient with multiple myeloma and monoclonal cryoglobulinaemia who developed a severe haemolytic anaemia following a cytomegalovirus infection is reported. The presence of a high titre of anti-'i' cold antibody of IgM subclass is demonstrated. Anti-'i' antibody disappeared when complement-fixation antibody titres against cytomegalovirus decreased. Various pathogenetic mechanisms involved in the development of haemolytic anaemia associated with cytomegalovirus infection are discussed. To our knowledge, this is the first case described in the English language publications associating severe haemolytic anaemia with an anti-'i' antibody after a cytomegalovirus infection in an immunocompromised patient.

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Year:  1990        PMID： 2164663      PMCID： PMC2426850          DOI： 10.1136/pgmj.66.775.392

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  11 in total

1.  INFECTIOUS MONONUCLEOSIS: AN UNSUSPECTED SOURCE ON ANTI-I.

Authors:  W J JENKINS; H G KOSTER; W L MARSH; R L CARTER
Journal:  Br J Haematol       Date:  1965-07       Impact factor: 6.998

Review 2.  Diseases produced by cytomegaloviruses.

Authors:  G A Nankervis; M L Kumar
Journal:  Med Clin North Am       Date:  1978-09       Impact factor: 5.456

3.  Immunologic abnormalities induced by postperfusion cytomegalovirus infection.

Authors:  G L Kantor; L S Goldberg; B L Johnson; M M Derechin; E V Barnett
Journal:  Ann Intern Med       Date:  1970-10       Impact factor: 25.391

4.  Cytomegalovirus hepatitis in the adult.

Authors:  P J Toghill; M E Bailey; R Williams; R Zeegen; R Bown
Journal:  Lancet       Date:  1967-06-24       Impact factor: 79.321

5.  Cytomegalic inclusion-body disease associated with acquired autoimmune haemolytic anaemia.

Authors:  R R Coombs
Journal:  Br Med J       Date:  1968-06-22

6.  Etiology and pathogenesis of acquired hemolytic anemia.

Authors:  W W Zuelzer; C S Stulberg; R H Page; J Teruya; A J Brough
Journal:  Transfusion       Date:  1966 Sep-Oct       Impact factor: 3.157

Review 7.  Syndromes of cytomegalovirus infection.

Authors:  R F Betts
Journal:  Adv Intern Med       Date:  1980

8.  Improved survival times in multiple myeloma treated with melphalan, prednisone, cyclophosphamide, vincristine and BCNU: M-2 protocol.

Authors:  D C Case; D J Lee; B D Clarkson
Journal:  Am J Med       Date:  1977-12       Impact factor: 4.965

9.  Anti-"i" antibody and hemolytic anemia associated with spontaneous cytomegalovirus mononucleosis.

Authors:  B S Berlin; R Chandler; D Green
Journal:  Am J Clin Pathol       Date:  1977-05       Impact factor: 2.493

10.  A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival.

Authors:  B G Durie; S E Salmon
Journal:  Cancer       Date:  1975-09       Impact factor: 6.860
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  1 in total

1.  A Case of Multiple Myeloma Presenting with Gastrointestinal Bleeding and Evans Syndrome.

Authors:  Muhammad S Khan; Rahil Kasmani; Ghazal Khan; Khalid Changal; Hemindermeet Singh
Journal:  Cureus       Date:  2019-10-22
  1 in total

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