| Literature DB >> 21645780 |
Sonia Sheikh1, Christophe Blaszykowski, Michael Thompson.
Abstract
Herein is described a label-free immunosensor dedicated to the detection of HIV-2. The biosensor platform is constructed as a mixed self-assembled monolayer-coated quartz wafer onto which HIV-2 immunodominant epitopes are immobilized. The biosensing properties, in terms of specific vs. non-specific antigen-antibody interactions, are evaluated with the electromagnetic piezoelectric acoustic sensor (EMPAS) using equimolar serum solutions of HIV-2 or HIV-1 monoclonal antibodies, respectively. This immunosensor constitutes the first real-world application of the EMPAS technology in the bioanalytical field.Entities:
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Year: 2011 PMID： 21645780 DOI： 10.1016/j.talanta.2011.04.008
Source DB: PubMed Journal: Talanta ISSN： 0039-9140 Impact factor: 6.057