BACKGROUND: Cases of cytomegalovirus colitis are exceptionally reported in immuno-competent infant. The pathogenesis is uncertain but breast-feeding is considered as a main source of postnatal infection. CASE PRESENTATION: Here we report a full-term, formula-fed infant who developed a severe cytomegalovirus anaemia and colitis when aged 2 months. CONCLUSION: Even if the molecular identity between the cytomegalovirus-isolate of the infant and the maternal virus could not be demonstrated, we confirmed through laboratory investigation that cytomegalovirus infection was acquired postnatally. However, the source of cytomegalovirus infection remained unclear. Alternative modes of cytomegalovirus transmission are discussed.
BACKGROUND: Cases of cytomegalovirus colitis are exceptionally reported in immuno-competent infant. The pathogenesis is uncertain but breast-feeding is considered as a main source of postnatal infection. CASE PRESENTATION: Here we report a full-term, formula-fed infant who developed a severe cytomegalovirusanaemia and colitis when aged 2 months. CONCLUSION: Even if the molecular identity between the cytomegalovirus-isolate of the infant and the maternal virus could not be demonstrated, we confirmed through laboratory investigation that cytomegalovirus infection was acquired postnatally. However, the source of cytomegalovirus infection remained unclear. Alternative modes of cytomegalovirus transmission are discussed.
Authors: R E Quiros-Tejeira; M E Ament; T Rivera-Penera; G Cortina; J H Vargas Journal: J Pediatr Gastroenterol Nutr Date: 1999-07 Impact factor: 2.839
Authors: B Ghidini; M Bellaiche; D Berrebi; J Viala; J P Hugot; J F Mougenot; A Munck; M Peuchmaur; J P Cezard Journal: Gut Date: 2006-04 Impact factor: 23.059
Authors: P S Buonuomo; P Maurizi; P Valentini; S Mastrangelo; I Lazzareschi; V Ridola; R Riccardi Journal: J Perinatol Date: 2006-10 Impact factor: 2.521
Authors: Min Ji Jin; Yunkyum Kim; Eun Mi Choi; Ye Jee Shim; Heung Sik Kim; Jin Kyung Suh; Ji Yoon Kim; Kun Soo Lee; Sun Young Park; Jae Min Lee; Jeong Ok Hah Journal: Blood Res Date: 2018-06-25