Literature DB >> 21645122

The diagnosis of early psoriatic arthritis in an outpatient dermatological centre for psoriasis.

C Bonifati1, F Elia, F Francesconi, F Ceralli, S Izzi, F M Solivetti, C De Mutiis.   

Abstract

BACKGROUND: Most of the data currently available on early psoriatic arthritis (EPsA) derive from studies performed in rheumatological settings. However, in recent years, there has been an increase in the amount of data from dermatologic centres.
OBJECTIVES: To describe the prevalence, clinical, laboratory and imaging characteristics of psoriatic patients with EPsA seen at a dermatological outpatient psoriasis centre.
METHODS: From January 2007 to May 2010, all patients with psoriasis who visited the psoriasis centre were asked about inflammatory joint involvement. A diagnosis of psoriatic arthritis was made on the basis of clinical, laboratory and imaging studies. The patients were diagnosed with early PsA (EPsA) if their inflammatory articular symptoms had been present for ≤ 1 year.
RESULTS: We diagnosed EPsA in 33 patients. Joint involvement was polyarticular (>5 joints involved) in 20 patients (60.6%) and oligoarticular (≤5 joints involved) in the remaining 13 patients. Quality of life due to skin involvement and the degree of functional impairment due to joint inflammation were only mildly affected, as measured by DLQI and HAQ, respectively. A direct correlation between the number of tender joints (ACR 68) and HAQ was found (r = 0.36; P = 0.04). Imaging studies showed that in spite of the absence of radiologic findings of peripheral joint damage, ultrasonography and contrast enhanced ultrasonography showed signs of articular inflammation in all patients.
CONCLUSIONS: A diagnosis of EPsA can be correctly performed in a dermatologic outpatient facility. To do so, a close collaboration among dermatologists, rheumatologists and radiologists is necessary.
© 2011 The Authors. Journal of the European Academy of Dermatology and Venereology © 2011 European Academy of Dermatology and Venereology.

Entities:  

Mesh:

Year:  2011        PMID: 21645122     DOI: 10.1111/j.1468-3083.2011.04138.x

Source DB:  PubMed          Journal:  J Eur Acad Dermatol Venereol        ISSN: 0926-9959            Impact factor:   6.166


  4 in total

Review 1.  Epidemiology of Psoriasis and Psoriatic Arthritis in Italy-a Systematic Review.

Authors:  Francesca Prignano; Veronica Rogai; Elisabetta Cavallucci; Alessandro Bitossi; Volker Hammen; Fabrizio Cantini
Journal:  Curr Rheumatol Rep       Date:  2018-05-30       Impact factor: 4.592

Review 2.  Managing patients with psoriatic disease: the diagnosis and pharmacologic treatment of psoriatic arthritis in patients with psoriasis.

Authors:  Philip J Mease; April W Armstrong
Journal:  Drugs       Date:  2014-03       Impact factor: 9.546

3.  Clinical and Contrast-Enhanced Ultrasound Echography Outcomes in Psoriatic Arthritis Patients after One Year of Continuous Therapy with Anti-TNF Drugs.

Authors:  Claudio Bonifati; Fulvia Elia; Dario Graceffa; Fabrizio Ceralli; Elisa Maiani; Carlo De Mutiis; Francesco M Solivetti
Journal:  ISRN Dermatol       Date:  2014-02-06

Review 4.  Axial Psoriatic Disease: Clinical and Imaging Assessment of an Underdiagnosed Condition.

Authors:  Ivan Giovannini; Alen Zabotti; Carmelo Cicciò; Matteo Salgarello; Lorenzo Cereser; Salvatore De Vita; Ilaria Tinazzi
Journal:  J Clin Med       Date:  2021-06-27       Impact factor: 4.241

  4 in total

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